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Dibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalThrough enhancing osteogenesis at the site of implantation, dibotermin alfa accelerates the healing of open tibial shaft fractures and reduces the need for secondary intervention [A31945]. … In a prospective clinical study of patients with an open tibial fracture, administration of dibotermin alfa resulted in faster fracture- or wound-healing, significantly fewer secondary invasive interventions
Elasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigational[L28026] A phase I, open-label, dose-ranging clinical trial (NCT04283461) was initiated in March 2020 in which 45 subjects received two intramuscular doses (on days 1 and 29).
Risankizumab
go.drugbank.com/drugs/DB14762ApprovedInvestigational[L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.
Butriptyline
go.drugbank.com/drugs/DB09016ApprovedWithdrawnButriptyline is a tricyclic antidepressant which has been used in Europe since 1974. It is the isobutyl side chain homologue of amitriptyline.
Inositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnInositol nicotinate is prescribed in Europe under the name Hexopal as a symptomatic treatment for severe intermittent claudication and Raynaud’s phenomenon.
Daridorexant
go.drugbank.com/drugs/DB15031ApprovedInvestigational[A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin receptor antagonist approved in the market,[L41725] and by Health Canada on April 26, 2023.
Befunolol
go.drugbank.com/drugs/DB09013ExperimentalIt is currently in experimental status, and is being tested for the management of open angle glaucoma.
Safinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalIt was approved in Europe in February 2015, and in the United States on March 21, 2017.
Protokylol
go.drugbank.com/drugs/DB06814ApprovedVet approvedProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
Talc
go.drugbank.com/drugs/DB09511ApprovedInvestigationalTalc is a mineral composed primarily of magnesium, silicon and oxygen. It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders. Talc helps absorb moisture, fres...