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Simethicone
go.drugbank.com/drugs/DB09512ApprovedInvestigational[A228308] It has a favourable safety profile as it is not systemically absorbed.[A228308] Simethicone has been in use since the 1940s[A228303] but was granted FDA approval in 1952.[A228308]
Mixtures: E-Z-GAS II GRANULES, SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 90 ADETProducts: SIMETICONE EG, Simcone-T Sugar Free Chewable Tablet 80mgBiperiden
go.drugbank.com/drugs/DB00810ApprovedInvestigationalWithdrawnIt has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. … It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Synonyms: 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanolProducts: AKINETON 4MG, AKINETON 4MG RETARDNilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Products: ESCOR 8MG RETARDKAPSELN, Tensan retard 8 mg - KapselnTolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Products: Mylan-tolterodine ER, TOLTERODIN HEXAL RET 4 MGMegestrol acetate
go.drugbank.com/drugs/DB00351ApprovedInvestigationalVet approvedAs the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Products: Megace ES, Megace EsDextrothyroxine
go.drugbank.com/drugs/DB00509ApprovedWithdrawnThe major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobul...
Products: Choloxin Tablet 4mg, Choloxin - Tab 4mgGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalIt is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs. … It is commonly marketed under the brand name Amaryl as oral tablets and is typically administered once daily.
Mixtures: AMARYL®M 1 MG/ 500 MG, AMARYL®M 4 MG/ 1000 MGProducts: GLIMEPIRID - CT 4MG, GLIMEPIRID HEUMANN 4MG NETCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalIt may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease. … It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract.
Mixtures: CAMLOSTAR 8MG/5MG, CAMLOSTAR 8MG/5MGProducts: ATACAND 4MG, CANDESARTAN EGIxazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigationalBecause it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor.[A7948] More than 99% of the drug compound is the R-enantiomer. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.
Products: NINLARO CAPSULE 4mg, Ninlaro Hard Capsule 4mgLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A174553] More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid … [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day
Products: LOVASTATINA EG, LOSTIN® 20 MG