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Displaying results 71 - 80 of 4358 in total
  1. Target

    Voltage-dependent L-type calcium channel

    go.drugbank.com/bio_entities/BE0008715
    TargetTransporterHumans

    Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group … The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation

    Polypeptides: Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1DSynonyms: Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-gated calcium channel subunit alpha Cav1.3
  2. Target

    Voltage-dependent T-type calcium channel

    go.drugbank.com/bio_entities/BE0008716
    TargetTransporterHumans

    Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. … Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H

    Polypeptides: Voltage-dependent T-type calcium channel subunit alpha-1G, Voltage-dependent T-type calcium channel subunit alpha-1HSynonyms: Voltage-gated calcium channel subunit alpha Cav3.1, Voltage-gated calcium channel subunit alpha Cav3.2
  3. Target

    Voltage-dependent R-type calcium channel

    go.drugbank.com/bio_entities/BE0008718
    TransporterTargetHumans

    Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells (PubMed:30343943). … R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP).

    Polypeptides: Voltage-dependent R-type calcium channel subunit alpha-1ESynonyms: Voltage-gated calcium channel subunit alpha Cav2.3
  4. Target

    Voltage-dependent N-type calcium channel

    go.drugbank.com/bio_entities/BE0009351
    TargetHumans

    N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling (PubMed:25296916). … The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.

    Polypeptides: Voltage-dependent calcium channel subunit alpha-2/delta-1, Voltage-dependent calcium channel subunit alpha-2/delta-2Synonyms: Voltage-gated calcium channel subunit alpha-2/delta-1, Voltage-gated calcium channel subunit alpha-2/delta-2
  5. Drug

    Perindopril

    go.drugbank.com/drugs/DB00790
    ApprovedInvestigational

    Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration....

    Mixtures: PERINDOPRIL E AMLODIPINA DOC GENERICI, PERINDOPRIL E AMLODIPINA DOC GENERICIProducts: COVEREX-AS, PERINDOPRIL MYLAN GENERICS
  6. Drug

    Miconazole

    go.drugbank.com/drugs/DB01110
    ApprovedInvestigationalVet approved

    Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. … [A214523, L14021] It is currently available as a variety of prescription and over the counter products.

    Products: Vagisil Brand Vagistat
  7. Target

    Voltage-gated inwardly rectifying potassium channel KCNH6

    go.drugbank.com/bio_entities/BE0000462
    TargetHumans

    Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel.

    Polypeptides: Voltage-gated inwardly rectifying potassium channel KCNH6Synonyms: Voltage-gated potassium channel subunit Kv11.2, Potassium voltage-gated channel subfamily H member 6
  8. Target

    Non-selective voltage-gated ion channel VDAC1

    go.drugbank.com/bio_entities/BE0002468
    TargetHumans

    Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane (PubMed:10661876, PubMed:11845315, PubMed:18755977

    Polypeptides: Non-selective voltage-gated ion channel VDAC1Synonyms: Voltage-dependent anion-selective channel protein 1
  9. Target

    Voltage-dependent calcium channel gamma-2 subunit

    go.drugbank.com/bio_entities/BE0005108
    TargetHumans

    Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deacti...

    Polypeptides: Voltage-dependent calcium channel gamma-2 subunitSynonyms: Neuronal voltage-gated calcium channel gamma-2 subunit
  10. Target

    Voltage-gated delayed rectifier potassium channel KCNH1

    go.drugbank.com/bio_entities/BE0005191
    TargetHumans

    Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel that mediates outward-rectifying potassium currents which, on depolarization, reaches a steady-state level and do not

    Polypeptides: Voltage-gated delayed rectifier potassium channel KCNH1Synonyms: Voltage-gated potassium channel subunit Kv10.1, Potassium voltage-gated channel subfamily H member 1