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Displaying results 8041 - 8050 of 10000 in total
  1. Drug

    Inositol 1,3-bisphosphate

    go.drugbank.com/drugs/DB02942
    Experimental

    Inositol 1,3-bisphosphate is a phosphorylated myo-inositol derivative and small molecule metabolite in which phosphate groups occupy the 1 and 3 positions of the inositol ring. … The compound corresponds to the soluble headgroup of phosphatidylinositol 3-phosphate (PtdIns(3)P), an endosomal signaling lipid recognized by FYVE domains, and it has been used as a ligand in structural

  2. Drug

    Loprazolam

    go.drugbank.com/drugs/DB13643
    Experimental

    It is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug. … It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.

  3. Drug

    Isoaminile

    go.drugbank.com/drugs/DB08944
    ApprovedWithdrawn

    Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties.

  4. Drug

    GI-181771X

    go.drugbank.com/drugs/DB12309
    Experimental

    Gski181771 X is under investigation in clinical trial NCT00600743 (Effect of a CCK-1R Agonist on Food Intake in Humans).

    Categories: Receptor, Cholecystokinin A, agonists
  5. Drug

    Fletikumab

    go.drugbank.com/drugs/DB12356
    Investigational

    Fletikumab is under investigation in clinical trial NCT01038674 (Safety and Tolerability of Anti-IL-20 in Subjects With Rheumatoid Arthritis).

    Synonyms: Anti-IL-20
  6. Drug

    Q-Derp1

    go.drugbank.com/drugs/DB05857
    Experimental

    Q-Derp1 is developed by Cytos Biotechnology as an immunodrug. It is an antigen for the prevention of various major chronic diseases. Derp1 is the dominant allergic protein found in dust mite feces.

  7. Drug

    MORAb-066

    go.drugbank.com/drugs/DB17347
    Investigational

    MORAb-066 is a humanized antibody directed against tissue factor (TF). It is being investigated in pancreatic cancer.

  8. Drug

    Barbital

    go.drugbank.com/drugs/DB01483
    ExperimentalIllicit

    Barbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug. … A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence.

  9. Drug

    Rimacalib

    go.drugbank.com/drugs/DB12571
    Investigational

    Rimacalib has been used in trials studying the treatment of Rheumatoid Arthritis (RA).

  10. Drug

    ONT-093

    go.drugbank.com/drugs/DB14069
    Experimental

    In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics. … ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp).