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Displaying results 801 - 810 of 7452 in total
  1. Drug

    Gabexate

    go.drugbank.com/drugs/DB12831
    Investigational

    Gabexate has been investigated for use in cancer, ischemia-reperfusion injury, and pancreatitis.[A19218,A19219,A19220]

    Products: FOY
  2. Indication

    Sickle Cell Disease

    go.drugbank.com/conditions/DBCOND0029334
    Drugs: Exagamglogene autotemcel · Lovotibeglogene autotemcel · Piracetam · Voxelotor
    Synonyms: Double heterozygous for Hb S and Hb D, Hereditary hemoglobinopathy disorder homozygous for hemoglobin S
  3. Target

    Protein c-Fos

    go.drugbank.com/bio_entities/BE0001126
    TargetHumans

    In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. … Has a critical function in regulating the development of cells destined to form and maintain the skeleton.

    Polypeptides: Protein c-FosSynonyms: Cellular oncogene fos, Proto-oncogene c-Fos
  4. Drug

    Zilucoplan

    go.drugbank.com/drugs/DB15636
    ApprovedInvestigational

    [A261841] On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of generalized myasthenia gravis. … [L48701] It was also later approved by the EMA on December 4, 2023, as an add-on treatment for the same condition.[L49131] In July 2024, it was approved by Health Canada for the same indication.

  5. Indication

    Peripheral T-Cell Lymphoma (PTCL)

    go.drugbank.com/conditions/DBCOND0079798
    Drugs: Brentuximab vedotin
    Synonyms: Peripheral T-cell lymphoma, no International Classification of Diseases for Oncology subtype
  6. Indication

    Generalized Myasthenia Gravis

    go.drugbank.com/conditions/DBCOND0037937
    Drugs: Eculizumab · Efgartigimod alfa · Hyaluronidase (human recombinant) · Inebilizumab · Nipocalimab · Ravulizumab +2 more
    Synonyms: Myasthenia Gravis Generalized, Myasthenia Gravis, Generalized
  7. Drug

    Sulfadoxine

    go.drugbank.com/drugs/DB01299
    ApprovedInvestigationalWithdrawn

    A long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.

  8. Drug

    Desloratadine

    go.drugbank.com/drugs/DB00967
    ApprovedInvestigational

    Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a l...

    Categories: Antihistamines for Systemic UseProducts: ALLEX
  9. Drug

    Olezarsen

    go.drugbank.com/drugs/DB18728
    ApprovedInvestigational

    [L52033] On December 19, 2024, olezarsen was approved by the FDA for the treatment of familial chylomicronemia syndrome.[L52028] It is also being investigated for the treatment of hyperlipidemia. … Olezarsen is an antisense oligonucleotide that targets the messenger RNA (mRNA) for apolipoprotein C-III (APOC3, apoC-III),[L52033] which is a key regulator of triglyceride levels in plasma, in the liver

    Categories: Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaSynonyms: ALL-P-AMBO-5'-O-(((6-(5-((TRIS(3-(6-(2-ACETAMIDO-2-DEOXY-.BETA.
  10. Target

    Lysosomal protective protein

    go.drugbank.com/bio_entities/BE0008657
    EnzymeHumans

    Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability

    Synonyms: Protective protein for beta-galactosidase