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Ammonium lactate
go.drugbank.com/drugs/DB06768ApprovedAmmonium lactate is the ammonium salt of lactic acid.
Efalizumab
go.drugbank.com/drugs/DB00095ApprovedWithdrawnHumanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medi...
Gestodene
go.drugbank.com/drugs/DB06730InvestigationalGestodene is a progestogen hormonal contraceptive. Products containing gestoden include Meliane, which contains 20 mcg of ethinylestradiol and 75 mcg of gestodene; and Gynera, which contains 30 mcg of ethinylestradiol and 75 mcg of gesto...
Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 SubstratesPrazepam
go.drugbank.com/drugs/DB01588ApprovedIllicitPrazepam is a benzodiazepine that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesLaronidase
go.drugbank.com/drugs/DB00090ApprovedInvestigationalHuman recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted ami...
Mianserin
go.drugbank.com/drugs/DB06148ApprovedWithdrawnA tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNafarelin
go.drugbank.com/drugs/DB00666ApprovedInvestigationalNafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.
Categories: Gonadotropin Releasing Hormone Receptor Agonist, Gonadotropin Releasing Hormone Receptor AgonistsAbarelix
go.drugbank.com/drugs/DB00106ApprovedWithdrawnSynthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Fluphenazine
go.drugbank.com/drugs/DB00623ApprovedA phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2D6 InhibitorsFramycetin
go.drugbank.com/drugs/DB00452ApprovedInvestigationalA component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)