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Ertiprotafib
go.drugbank.com/drugs/DB06521ExperimentalErtiprotafib belongs to a novel class of insulin sensitizers developed for treatment of type 2 diabetes. … In insulin-resistant rodent models, ertiprotafib and a close analog lowered both fasting blood glucose and insulin levels and improved glycemic excursion during an oral glucose tolerance test.
Categories: Heterocyclic Compounds, 1-Ringgamma-Butyrolactone
go.drugbank.com/drugs/DB04699ExperimentalIllicitOne of the furans with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. … It is also used as a pharmacological agent and solvent.
Categories: 4-Butyrolactone, Heterocyclic Compounds, 1-RingSynonyms: 4-butyrolactone, γ-butyrolactoneCOVID-19 convalescent plasma
go.drugbank.com/drugs/DB15692InvestigationalCOVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2. … [L14333] This investigational COVID-19 treatment is currently available through three main pathways: use in registered clinical trials, use through the expanded access COVID-19 protocol (21 CFR 312.305
Synonyms: anti-SARS-CoV-2 convalescent plasmaAVI-4020
go.drugbank.com/drugs/DB05873InvestigationalAVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus disease who have serious neurological impairment (WNV neuroinvasive disease).
Calanolide A
go.drugbank.com/drugs/DB04886InvestigationalCalanolide A is a new non-nucleoside reverse transcriptase inhibitor (NNRTI) derived from a plant found in the Malaysian rain forest. A related compound, calanolide B, also has anti-HIV activity. … A preliminary dosing study among HIV-infected individuals showed a significant antiviral effect compared with placebo.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: Calanolide A, (+)-calanolide APF-03758309
go.drugbank.com/drugs/DB11775InvestigationalPF-03758309 has been used in trials studying the treatment of Advanced Solid Tumors.
Categories: Heterocyclic Compounds, 1-RingDasolampanel etibutil
go.drugbank.com/drugs/DB12049InvestigationalDasolampanel etibutil has been used in trials studying the treatment of Diabetic Neuropathy, Painful.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRislenemdaz
go.drugbank.com/drugs/DB12063InvestigationalMk 0657 has been used in trials studying the treatment of Major Depressive Disorder.
Categories: Receptors, N-Methyl-D-Aspartate, antagonists & inhibitors, Heterocyclic Compounds, 1-RingAvoralstat
go.drugbank.com/drugs/DB12120InvestigationalAvoralstat has been used in trials studying the prevention of HAE and Hereditary Angioedema.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(2-((4-Carbamimidoylphenyl)carbamoyl)-4-ethenyl-5-methoxyphenyl)-6-((cyclopropylmethyl)carbamoyl)pyridine-2-carboxylic acid, 3-[2-(4-carbamimidoyl-phenylcarbamoyl)-5-methoxy-4-vinyl-phenyl]-6-(cyclopropylmethyl-carbamoyl)-pyridine-2-carboxylic acidBalicatib
go.drugbank.com/drugs/DB12239InvestigationalBalicatib has been used in trials studying the treatment of Osteoporosis and Knee Osteoarthritis.
Categories: Heterocyclic Compounds, 1-Ring