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Displaying results 8121 - 8130 of 10000 in total
  1. Drug

    BILR-355

    go.drugbank.com/drugs/DB33802
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    AZD0543

    go.drugbank.com/drugs/DB33982
    Experimental

    AZD0543 is a small molecule drug. AZD0543 is under investigation in clinical trial NCT07824622 (Study of Safety and PK of AZD0543 in Healthy Adults).

  3. Drug

    ATORM-C

    go.drugbank.com/drugs/DB33983
    Experimental

    ATORM-C is a biologic drug. ATORM-C is under investigation in clinical trial NCT07822087 (A Phase 1 Study of ATORM-C in Patients With Crohn's Disease).

    Synonyms: ATORM-C
  4. Drug

    Asparaginase Escherichia coli

    go.drugbank.com/drugs/DB00023
    ApprovedInvestigational

    Asparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … L-asparaginase of _E. coli_ is marketed under several different trade names, including Elspar, for the treatment of acute lymphoblastic leukemia (ALL) as part of a multi-agent chemotherapeutic regimen.

    Synonyms: L-Asnase, L-asparaginaseProducts: LEUNASE ENJEKTABL 10.000 IU FLAKON, 1 ADET
  5. Drug

    Pancrelipase

    go.drugbank.com/drugs/DB00085
    ApprovedInvestigational

    Pancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.

    Mixtures: FLATOL®, STAMYL®Products: MEZYM F, Pancrex V Powder
  6. Drug

    Daclizumab

    go.drugbank.com/drugs/DB00111
    ApprovedInvestigationalWithdrawn

    on 2 March 2018 [L1738]. … Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences.

    Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking Antibody
  7. Drug

    ATP

    go.drugbank.com/drugs/DB00171
    InvestigationalNutraceutical

    In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: Adenosine 5'-triphosphate, Adenosine-5'-triphosphate
  8. Drug

    Amphetamine

    go.drugbank.com/drugs/DB00182
    ApprovedIllicitInvestigational

    Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. … It was previously used for a large variety of conditions and this changed until this point where its use is highly restricted.

    Mixtures: Mixed Salts of a Single-Entity Amphetamine Product, Mixed Salts of a Single-Entity Amphetamine ProductCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Inhibitors
  9. Drug

    Nicotine

    go.drugbank.com/drugs/DB00184
    ApprovedInvestigational

    Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of it...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: (S)-3-(1-methylpyrrolidin-2-yl)pyridine, (S)-3-(N-methylpyrrolidin-2-yl)pyridine
  10. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in … In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850

    Mixtures: DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLETCategories: P-glycoprotein inhibitors, P-glycoprotein substrates