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Zandatrigine
go.drugbank.com/drugs/DB19051InvestigationalZandatrigine is under investigation in clinical trial NCT05226780 (Extension Study to Evaluate How Safe and Tolerable NBI-921352 Is as an Adjunctive Therapy for Participants With SCN8A-DEE).
Synonyms: Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3s)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-n-4-thiazolyl-Emrusolmin
go.drugbank.com/drugs/DB13927InvestigationalEmrusolmin restores hippocampal synaptic and transcriptional plasticity as well as spatial memory in a mouse model for Alzheimer's disease, when given orally before or after the onset of pathology.
Ceramide NP
go.drugbank.com/drugs/DB14111InvestigationalCeramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. … Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) [A27233]. It is widely used as a moisturizer in various cosmetic and personal products.
Synonyms: Cer(t18:0/18:1n-9), N-oleoylphytosphingosineAEF0117
go.drugbank.com/drugs/DB27675InvestigationalAEF0117 is a small molecule drug. AEF0117 is under investigation in clinical trial NCT05554926 (Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects).
Synonyms: 3ß-(4-methoxybenzyloxy)pregn-5-en-20-one, 3β-(4-methoxybenzyloxy)pregn-5-en-20-oneReloxaliase
go.drugbank.com/drugs/DB15560InvestigationalReloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria). … Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from _Bacillus Subtilis_.
Pegapamodutide
go.drugbank.com/drugs/DB14817InvestigationalPegapamodutide is under investigation in clinical trial NCT02188303 (A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants).
Icrucumab
go.drugbank.com/drugs/DB14824InvestigationalIcrucumab is under investigation in clinical trial NCT01111604 (A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer).
PF-5190457
go.drugbank.com/drugs/DB14870InvestigationalPF-5190457 is under investigation in clinical trial NCT01522807 (A Study Of Three PF-05190457 Formulations In Healthy Volunteers).
Pimitespib
go.drugbank.com/drugs/DB14876InvestigationalTAS-116 is under investigation in clinical trial NCT02965885 (A Study of TAS-116 in Patients With Solid Tumors).