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Drometrizole trisiloxane
go.drugbank.com/drugs/DB11585ApprovedThe compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia … Despite being used elsewhere in the world with relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as
Mixtures: Garnier Ombrelle Kids Wet N Protect Hypoallergenic SPF 45 Mexoryl Technology, Garnier Ombrelle Kids Wet N Protect Hypoallergenic SPF 45 Mexoryl TechnologyCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingIsotretinoin
go.drugbank.com/drugs/DB00982ApprovedInvestigational[L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574] … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.
Mixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELCategories: Retinoids for Topical Use in Acne, Cytochrome P-450 SubstratesBenzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalaspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties. … Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base.
Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML, KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 MLCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-SteroidalTicagrelor
go.drugbank.com/drugs/DB08816ApprovedInvestigational[A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.[A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. … Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.
Synonyms: (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diolCategories: P-glycoprotein inhibitors, P-glycoprotein substratesMetelimumab
go.drugbank.com/drugs/DB18695ExperimentalMetelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Synonyms: Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain)), disulfide with human monoclonal cat-192 .kappa.-chain, dimer, Human anti-transforming growth factor beta 1 monoclonal antibodyLinezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideCarbidopa
go.drugbank.com/drugs/DB00190ApprovedInvestigational[L5110] On the other hand, the combination treatment of carbidopa/levodopa was originally developed by Watson Labs but the historical information by the FDA brings back to the approval of this combination … An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.
Mixtures: LEVODO CA E P100/25/200, LEVODO CA E P100/25/200Categories: Aromatic L-amino Acid Decarboxylase InhibitorsTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.
Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dioneInternational brands: Omcilon-ACefprozil
go.drugbank.com/drugs/DB01150ApprovedInvestigationalCefprozil is a cephalosporin antibiotic that is commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others.
Categories: Heterocyclic Compounds, 2-RingProducts: Nu-cefprozil, Cefzil Powder for Oral Suspension-250 Mg/ 5 MlHepatorenal Syndrome Type 1
go.drugbank.com/conditions/DBCOND0047853Drugs: TerlipressinSynonyms: Hepatorenal Syndrome Type I