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Alteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigational[A252270] The use of alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and stenting. … [L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots.
Synonyms: t-PA, t-plasminogen activatorProducts: ACTILYSE 10 MG FLAKON, 1 ADET, ACTILYSE 50 MG FLAKON, 1 ADETDaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal … tryptophan covalently bonded to decanoic acid.
Products: CUBICIN 500 MG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 30 ADET, XAPTO 500 MG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADETOxazepam
go.drugbank.com/drugs/DB00842Approvedas compared to other benzodiazepines, and is likely owing in part to oxazepam's relatively simple metabolism. … Oxazepam, like related 3-hydroxybenzodiazepine [lorazepam], is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous
Products: OXAZEPAM-NEURAX 10 MG, PRAXITEN 10Hydroxyethyl Starch
go.drugbank.com/drugs/DB09106ApprovedInvestigationalHydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. … HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.
Mixtures: VOLUHES (HES 130/0.4) %6 IV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETLI, VOLUHES (HES 130/0.4) %6 IV İNFÜZYON İÇİN ÇÖZELTİ, 500 ML SETSIZProducts: HAES-STERIL %10 500 ML SOLUSYON, BIOHES %10 INTRAVENOZ 500 ML SOLUSYON SETLI SISENorfloxacin
go.drugbank.com/drugs/DB01059ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: นอร์ฟาน-100, นอร์ฟาส - 100Montelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalMontelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … [L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or complementary with the use of inhaled
International brands: Montelo-10Mixtures: LEVMONT 2.5/4 MG TOZ İÇEREN SAŞE, 90 ADET, LEVMONT 2.5/4 MG TOZ İÇEREN SAŞE, 30 ADETPyrantel
go.drugbank.com/drugs/DB11156ApprovedVet approvedPyrantel has shown to be effective after a single dose [L1905]. In humans, it is administered as pyrantel pamoate [A32282],[A32283],[L1893],[L1898]. … Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use as an anthelmintic drug
Mixtures: PAMOXPEN - PAMOATO DE PIRANTEL100 MG+ PAMOATO DE OXANTEL 100 MG TABLETAS, Heartgard Plus Chewable Tablet for Dogs - 51 - 100 lbsProducts: KONTIL 250 MG ÇIĞNEME TABLETI, 1000 ADET, KONTIL 250 MG ÇIĞNEME TABLETI, 500 ADETIdarucizumab
go.drugbank.com/drugs/DB09264ApprovedIdarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its … As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when given to patients at increased risk (elderly, chronic kidney disease
Products: PRAXBIND Solution for Injection/Infusion 50 mg/ml, PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/MLEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[A15202] By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces the delivery of intestinal cholesterol to the liver.[L11347] … [A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings
Mixtures: Rosamib 5 mg/10 mg Tabletten, Ezerosu 10 mg/5 mg-FilmtablettenCategories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 CYP3A InhibitorsDicloxacillin
go.drugbank.com/drugs/DB00485ApprovedInvestigationalVet approvedOne of the penicillins which is resistant to penicillinase.
Synonyms: (2S,5R,6R)-6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers