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Displaying results 811 - 820 of 10000 in total
  1. Drug

    Amitriptyline

    go.drugbank.com/drugs/DB00321
    ApprovedInvestigational

    Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]

    Mixtures: โพลีบอน 4-10, Etrafon 2 10Categories: Analgesics, Non-Narcotic, Non-Selective Monoamine Reuptake Inhibitors
  2. Drug

    VO659

    go.drugbank.com/drugs/DB18160
    Investigational

    VO659 is an antisense oligonucleotide being investigated for the treatment of Huntington's disease.

    Synonyms: an antisense oligonucleotide that has been developed to target expanded CAG repeats in messenger ribonucleic acid (mRNA)
  3. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178948,A178969] Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and increasing uveoscleral outflow. … [A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease.

    Mixtures: NEFRIDAXEM B+D, Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4%Categories: Sympathomimetics in Glaucoma Therapy, Heterocyclic Compounds, 2-Ring
  4. Target

    Calcium/calmodulin-dependent protein kinase type 1

    go.drugbank.com/bio_entities/BE0009417
    TargetHumans

    In vitro phosphorylates CREB1, ATF1, CFTR, MYL9 and SYN1/synapsin I … Upon NMDA receptor-mediated Ca(2+) elevation, promotes dendritic growth in hippocampal neurons and is essential in synapses for full long-term potentiation (LTP) and ERK2-dependent translational activation

    Synonyms: CaM kinase I, CaM kinase I alpha
  5. Indication

    Sezary Syndrome

    go.drugbank.com/conditions/DBCOND0001518
    Drugs: Doxorubicin · Isotretinoin · Pentostatin
    Synonyms: Cutaneous T-cell lymphoma, no ICD-O subtype, Cutaneous T-cell lymphoma, no International Classification of Diseases for Oncology subtype
  6. Indication

    Squamous Cell Carcinoma (SCC)

    go.drugbank.com/conditions/DBCOND0043488
    Drugs: Bleomycin
    Synonyms: Squamous cell carcinoma, no ICD-O subtype, Squamous cell carcinoma, no International Classification of Diseases for Oncology subtype
  7. Drug

    Bemotrizinol

    go.drugbank.com/drugs/DB11206
    Approved

    Bemotrizinol, or bis-ethylhexyloxyphenol methoxyphenyl triazine, is an organic UV filter found in over-the-counter sunscreen products. It primarily absorbs UV-A rays. … It is claimed to be photostable, which increases its onset of action and its efficiency in providing protection against UV-rays upon topical application [A19212, A32909].

    Mixtures: Dpc Pink Aura Cushion No.21, Dpc Pink Aura Cushion No.23Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Amiodarone

    go.drugbank.com/drugs/DB01118
    ApprovedInvestigational

    Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved for its approved indications, according to prescribing information.[L3561,L11265,L11286] … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.

    Categories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexSynonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
  9. Drug

    Diethylamino hydroxybenzoyl hexyl benzoate

    go.drugbank.com/drugs/DB11269
    Approved

    Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated … It is used in concentrations up to 10% in sunscreen products, either alone or in combination with other UV absorbers [F107].

    Mixtures: D-one By Tamdoan Bb Light, D-one By Tamdoan Bb MediumSynonyms: Hexyl 2-(4-(diethylamino)-2-hydroxybenzoyl)benzoate
  10. Drug

    Pidolic acid

    go.drugbank.com/drugs/DB03088
    ApprovedInvestigational

    Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics … Although pidolic acid is included in some over-the-counter, non-prescription dietary supplements for the proposed purpose of facilitating cognitive or memory enhancement, most available research suggest

    Mixtures: 2% Salicylic Acid FACIAL CLEANSERCategories: Heterocyclic Compounds, 1-Ring