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Dihydroorotate dehydrogenase A (fumarate)
go.drugbank.com/bio_entities/BE0002008TargetLactococcus lactis subsp. cremorisCatalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
Polypeptides: Dihydroorotate dehydrogenase A (fumarate)Synonyms: DHOD ABCL11 transcription factor A
go.drugbank.com/bio_entities/BE0019545TargetHumansMay function as a modulator of the transcriptional repression activity of NR2F2 (By similarity) … May play a role in hematopoiesis (By similarity). Essential factor in lymphopoiesis required for B-cell formation in fetal liver (By similarity).
Polypeptides: BCL11 transcription factor ACholecystokinin receptor type A
go.drugbank.com/bio_entities/BE0000402TargetHumansThis receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system … Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system.
Polypeptides: Cholecystokinin receptor type ASynonyms: CCK-A receptorCholine-phosphate cytidylyltransferase A
go.drugbank.com/bio_entities/BE0000615EnzymeTargetHumansCatalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis
Polypeptides: Choline-phosphate cytidylyltransferase ASynonyms: CT A, CCT ACatabolite control protein A
go.drugbank.com/bio_entities/BE0001530TargetBacillus megateriumGlobal transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
Polypeptides: Catabolite control protein AFructose-bisphosphate aldolase A
go.drugbank.com/bio_entities/BE0001683TargetEnzymeHumansIn addition, also functions as a scaffolding protein (By similarity). … Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (PubMed:14766013).
Polypeptides: Fructose-bisphosphate aldolase AOuter membrane protein A
go.drugbank.com/bio_entities/BE0002043TargetEscherichia coli (strain K12)Plays a role in resistance to environmental stress, and a role in outer membrane functionality and cell shape (PubMed:11906175, PubMed:361695). … A very abundant protein, there can be up to 210,000 OmpA molecules per cell (PubMed:24766808).
Polypeptides: Outer membrane protein ASynonyms: Outer membrane porin ADNA gyrase subunit A
go.drugbank.com/bio_entities/BE0003724TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.
Polypeptides: DNA gyrase subunit ADNA gyrase subunit A
go.drugbank.com/bio_entities/BE0008387TargetBacillus subtilis (strain 168)A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.
Polypeptides: DNA gyrase subunit A