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MK-0354

MK-0354, is an orally administered drug candidate under development by Merck for the treatment of atherosclerosis and related disorders.

SO-101

SO-101(Silenor) is a low-dose oral tablet formulation of doxepin hydrochloride that is patent protected for its use in insomnia. … Doxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.

4'-Methylene-5,8,10-trideazaaminopterin

CH-1504 is a an antirheumatic agent that has been shown in vitro to be a nonpolyglutamylatable and nonhydroxylatable antifolate that is more efficiently taken up into cells by the reduced folate carrier

Alfaxalone

Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic.

Lomerizine

Lomerizine is a diphenylmethylpiperazine calcium channel blocker[A245378, A245383] with relatively selective central nervous system (CNS) effects. … [A245383] This drug is used to prophylactically treat migraines[A245368, A245373] and is also being investigated against eye-related diseases that are associated with local circulatory disturbances, an

AVR-RD-01

AVR-RD-01 is an investigational _ex vivo_ lentiviral gene therapy developed by AVROBIO Inc. … It consists of autologous CD34+ cells that transduced with Lentiviral Vector/alpha-galactosidase A (AGA) encoding for the human AGA complementary deoxyribonucleic acid (cDNA) sequence.

Efavaleukin alfa

Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker.

Avasopasem manganese

Avasopasem manganese, also known as GC4419, is a highly-selective small molecule mimetic of superoxide dismutase (SOD) being investigated for the reduction of radiation-induced severe oral mucositis.

beta-Alanine

A rare genetic disorder, hyper-beta-alaninemia, has been reported. … beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine].

TAS-108