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Etofibrate
go.drugbank.com/drugs/DB08983ExperimentalEtofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin.
Etifoxine
go.drugbank.com/drugs/DB08986ApprovedWithdrawnIt is more effective than lorazepam as an anxiolytic, and has fewer side effects. Etifoxine has been associated with acute liver injury. … Etifoxine is an anxiolytic and anticonvulsant drug developed by Hoechst in the 1960s. It is used in anxiety disorders and to promote peripheral nerve healing.
Categories: Heterocyclic Compounds, 1-RingProducts: EXSIST® CAPSULASEtamivan
go.drugbank.com/drugs/DB08989ApprovedWithdrawnEtamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.
Epirizole
go.drugbank.com/drugs/DB08991ExperimentalEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 4-methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidineDitazole
go.drugbank.com/drugs/DB08994ApprovedWithdrawnAdditionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas. … Ditazole is a non-steroidal anti-inflammatory drug (NSAID). Ditazole's analgesic and antipyretic effects are similar to phenylbutazone.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanolBarbexaclone
go.drugbank.com/drugs/DB09001ExperimentalSeveral reports from Spanish and Italian literature suggest that barbexaclone is at least as effective as phenobarbital in adults and children, while being better tolerated and having less sedative properties … Barbexaclone, a salt compound of propylhexedrine and phenobarbital, is a potent antiepileptic. By weight, barbexaclone is 40% propylhexedrine and 60% phenobarbital.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersClocapramine
go.drugbank.com/drugs/DB09003ExperimentalClocapramine has been implicated in at least one strange death, including a suicide. … Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia.
Categories: Heterocyclic Compounds, 3-RingBeclamide
go.drugbank.com/drugs/DB09011ExperimentalBeclamide (N-benzyl-B-chloropropionamide) is a no longer used drug that possesses anticonvulsant and sedative activity.
Brotizolam
go.drugbank.com/drugs/DB09017ApprovedWithdrawnBrotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects. … Brotizolam has similar effects to short-acting benzodiazepines such as triazolam. Brotizolam is indicated for 2-4 weeks of treatment for severe or debilitating insomnia.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingInternational brands: Brotizolam MNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] It is also available in combination with [relatlimab] under the brand name Opdualag.[L41265,L49996,L50001]
Mixtures: OPDUALAG® SOLUCION INYECTABLECategories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors