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LB-100
go.drugbank.com/drugs/DB15412InvestigationalLB-100 is under investigation in clinical trial NCT03886662 (A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)).
Anivamersen
go.drugbank.com/drugs/DB16089InvestigationalAnivamersen is under investigation in clinical trial NCT01848106 (A Study to Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI).
Dimethandrolone Undecanoate
go.drugbank.com/drugs/DB16141InvestigationalDimethandrolone Undecanoate is under investigation in clinical trial NCT03455075 (Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal Men).
Pimicotinib
go.drugbank.com/drugs/DB18972InvestigationalIt was initially developed by Abbisko Therapeutics Co in collaboration with Merck KGaA. [L53748] Pimicotinib was granted Fast Track Designation in December 2023 by the FDA. [L53753] … Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).
Synonyms: 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-, 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamideNelutroctiv
go.drugbank.com/drugs/DB21554InvestigationalNelutroctiv is a small molecule drug. Nelutroctiv is under investigation in clinical trial NCT05662215 (A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants).
Porphobilinogen
go.drugbank.com/drugs/DB02272ExperimentalPorphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Clinofibrate
go.drugbank.com/drugs/DB09006ExperimentalClinofibrate is a fibrate drug sold and marketed in Japan.
Bicuculline
go.drugbank.com/drugs/DB11562ExperimentalIt was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors.
Londamocitinib
go.drugbank.com/drugs/DB19190InvestigationalLondamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high
Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-Lanabecestat
go.drugbank.com/drugs/DB14814InvestigationalLanabecestat is under investigation in clinical trial NCT03499041 (A Study of LY3314814 in Participants With Liver Impairment).