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Displaying results 821 - 830 of 10000 in total
  1. Drug

    Letrozole

    go.drugbank.com/drugs/DB01006
    ApprovedInvestigational

    [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: LETROZOL 1A PHARMA 2.5MG, LETROZOLO EG
  2. Drug

    Pentosan polysulfate

    go.drugbank.com/drugs/DB00686
    ApprovedInvestigational

    Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.

    Synonyms: (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULFATE, (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULPHATEProducts: MISURE ® GEL, MENTOSANIL®
  3. Drug

    Olmesartan

    go.drugbank.com/drugs/DB00275
    ApprovedInvestigational

    ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling. … In particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function.

    Mixtures: OLMEDOXTAN A®, OLMETAN® A 40/5 TABLETAS RECUBIERTASCategories: Angiotensin 2 Receptor Blocker
  4. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.

    Synonyms: Vitamin A Alcohol, all-trans-vitamin A alcoholInternational brands: Chocola A
  5. Target

    Voltage-gated Potassium Channels

    go.drugbank.com/bio_entities/BE0009847
    Target

    A-type voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes in the brain (PubMed:15454437). Mediates A-type current I(SA) in suprachiasmatic nucleus (SCN) neurons. Exhibits a low-threshol...

    Polypeptides: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Synonyms: Potassium voltage-gated channel subfamily E member 1-like protein
  6. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689].

    Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-D
  7. Pathway

    Antrafenine Anti-inflammatory Action Pathway

    smpdb.ca/view/SMP0124549
    Drug action

    Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase.

    Drugs: Glutathione · Dinoprostone · Calcium · Antrafenine · Mesoheme · Prostaglandin G2 +1 more
    Enzymes: Prostaglandin E synthase
  8. Pathway

    Nepafenac NSAID Action Pathway

    smpdb.ca/view/SMP0124581
    Drug action

    Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.

    Drugs: Glutathione · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 · Arachidonic Acid +2 more
    Enzymes: Prostaglandin E synthase
  9. Pathway

    Lornoxicam NSAID Action Pathway

    smpdb.ca/view/SMP0124587
    Drug action

    Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.

    Drugs: Glutathione · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 · Arachidonic Acid +1 more
    Enzymes: Prostaglandin E synthase
  10. Pathway

    Magnesium Salicylate NSAID Action Pathway

    smpdb.ca/view/SMP0124629
    Drug action

    Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase.

    Drugs: Glutathione · Dinoprostone · Calcium · Magnesium salicylate · Mesoheme · Prostaglandin G2 +1 more
    Enzymes: Prostaglandin E synthase