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Putative hydrolase DDAH2
go.drugbank.com/bio_entities/BE0000608TargetHumansPutative hydrolase with unknown substrate (Probable). Does not hydrolyze N(G),N(G)-dimethyl-L-arginine (ADMA) which acts as an inhibitor of NOS (PubMed:21493890, PubMed:37296100). In endothelial cells, induces expression of vascular endo...
Synonyms: S-phase proteinSuccinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
go.drugbank.com/bio_entities/BE0002256TargetEnzymeHumansKey enzyme for ketone body catabolism. Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate...
Synonyms: SCOT-sAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigationalAcetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.
Synonyms: (R)-2-acetylamino-3-mercaptopropanoic acid, L-α-acetamido-β-mercaptopropionic acidMixtures: Protect Plus SO 60, N-ACETILCISTEÍNA 2 G + GUAYACOLATO DE GLICERILO 2 G JARABEBenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. … [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259]
Synonyms: p-Carbethoxyaniline, Ethyl p-aminobenzoateMixtures: Coghlan s Sting Relief, Best Health Sore Throat Relief Cherry FlavorGrape seed oil
go.drugbank.com/drugs/DB14323InvestigationalGrape seed oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: European Grape Seed OilDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalAs a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. … Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies,
Synonyms: N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine, 2-(benzhydryloxy)-N,N-dimethylethylamineInternational brands: Dormarex 2Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. … It is sold under several brand names, most notably Tinactin and Odor Eaters.
Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl esterMixtures: PERMUT®, เดอมิกซ์-4Tick-Borne Encephalitis, European
go.drugbank.com/conditions/DBCOND0144103Synonyms: Tick-Borne Encephalitis, EuropeanKynurenine--oxoglutarate transaminase 1
go.drugbank.com/bio_entities/BE0000273TargetEnzymeHumansCatalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (PubMed:7883047)
Synonyms: Cysteine-S-conjugate beta-lyaseFunction: cysteine-S-conjugate beta-lyase activityHematopoietic prostaglandin D synthase
go.drugbank.com/bio_entities/BE0001167TargetHumansBifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide rang...
Synonyms: Glutathione S-transferase