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Ketotifen
go.drugbank.com/drugs/DB00920ApprovedInvestigationalavailable and indicated as an add-on therapy for children with atopic asthma. … [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of itchy eyes associated with allergies,[L32278] and in Canada a prescription-only oral formulation is
Products: KETOTIFENE EG, U-KEFEN TABLETS 1MGSertraline
go.drugbank.com/drugs/DB01104ApprovedInvestigationalDespite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects.
Synonyms: (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamineProducts: SERTRALINA EG, SERTRALINA EG STADAAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981. … [A235860,A235865] A meta-analysis of over 145,000 patients showed the risk of stroke in patients taking atenolol may depend on the age of the patient.
Mixtures: PLENACOR D, ATENOLOLO CLORTALIDONE EGProducts: ATENOLOLO EG, Nu-atenol Tab 50mgMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigational[A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.
Products: MIRTAZAPINA EG, Nu-mirtazapineOlmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigational[A174124,A178153,A173869,A185324,A185327,A185333,A185342,A185345] Like other ARBs, olmesartan blockade of RAAS slows the progression of diabetic nephropathy due to its renoprotective effects. … Olmesartan also affects the renin-angiotensin aldosterone system (RAAS), which plays an important role in hemostasis and regulation of kidney, vascular, and cardiac functions.
Mixtures: NORSAT-DUO, OLMEPRESS DCategories: Agents Acting on the Renin-Angiotensin SystemBosentan
go.drugbank.com/drugs/DB00559ApprovedInvestigationalBosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise pr...
Synonyms: 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide, p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamideProducts: N/A, TRACLEER ® 62.5 MG TABLETAS RECUBIERTAS DE PELICULA.Glimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalSUs due to minimal effects on ischemic preconditioning of cardiac myocytes. … First introduced in 1995, glimepiride is a member of the second-generation sulfonylurea (SU) drug class used for the management of type 2 diabetes mellitus (T2DM) to improve glycemic control.
Mixtures: GLIMETAL-DP, METGLITAL LEX 850/4 MG TABLETAS DE LIBERACIÓN PROLONGADACategories: Drugs Used in DiabetesCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalUnlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. … Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension.
Mixtures: CORIATROS DUO, CANDESARTAN COMP PU 8/12.5Categories: Agents Acting on the Renin-Angiotensin SystemAlbendazole
go.drugbank.com/drugs/DB00518ApprovedInvestigationalVet approved(From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Synonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamateInternational brands: Ben-A