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Phorbol 12-myristate 13-acetate diester
go.drugbank.com/drugs/DB17045InvestigationalPhorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).[A253087]
AAV-CNGB3
go.drugbank.com/drugs/DB18344InvestigationalAAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
DNL343
go.drugbank.com/drugs/DB18678InvestigationalDNL343 is under investigation in clinical trial NCT05842941 (HEALEY ALS Platform Trial - Regimen G DNL343).
CVN-424
go.drugbank.com/drugs/DB18958InvestigationalCVN-424 is under investigation in clinical trial NCT06006247 (Early Parkinson's Disease Monotherapy With CVN424).
Duvoglustat
go.drugbank.com/drugs/DB03206InvestigationalAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Plosaracetam
go.drugbank.com/drugs/DB21594InvestigationalPlosaracetam is under investigation in clinical trial NCT05199142 (A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive … The usage of the INN stem '-racetam' in the name indicates that Plosaracetam is a piracetam type amide type nootrope agent.
Istisociclib
go.drugbank.com/drugs/DB21703InvestigationalIstisociclib is under investigation in clinical trial NCT04718675 (A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer … The usage of the INN stem '-ciclib' in the name indicates that Istisociclib is a cyclin dependant kinase inhibitor.
Atirmociclib
go.drugbank.com/drugs/DB21733InvestigationalAtirmociclib is under investigation in clinical trial NCT06760637 (Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment … The usage of the INN stem '-ciclib' in the name indicates that Atirmociclib is a cyclin dependant kinase inhibitor.
Sulbutiamine
go.drugbank.com/drugs/DB13416InvestigationalThe chronic administration of the drug has demonstrated to improve long term memory formation in mice. … While its other uses include improvement of erectile dysfunction and reduction of psycho-behavioural inhibition, sulbutiamine showed evidence of modulatory effect on dopaminergic and glutamatergic cortical