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Norleucine
go.drugbank.com/drugs/DB15458InvestigationalNorleucine is under investigation in clinical trial NCT00081952 (Amino Acid Therapy for Hot Flashes in Postmenopausal Women).
Synonyms: L-NORLEUCINEAGG-523
go.drugbank.com/drugs/DB15460InvestigationalAGG-523 is under investigation in clinical trial NCT00380900 (Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy subjects and in subjects
Benzhydrocodone
go.drugbank.com/drugs/DB15465ApprovedBenzhydrocodone is a benzylic prodrug of hydrocodone.[L4894] It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse. … [A182177] Benzhydrocodone is indicated for use in the short-term management of pain.
Tallimustine
go.drugbank.com/drugs/DB15466ExperimentalTallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA. … [A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as [brostallicin], which have a favourable cytotoxicity
Zuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigationalZuranolone is a neuroactive steroid that acts as a positive allosteric modulator of the GABA<sub>A</sub> receptors. … This approval was based on favorable results from 2 phase 3 clinical trials.[L47691]
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingBOS172722
go.drugbank.com/drugs/DB15498InvestigationalBOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. … The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment, as its inhibition could lead to favorable effects.
Categories: Heterocyclic Compounds, 1-RingInfluenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (propiolactone inactivated)
go.drugbank.com/drugs/DB15500ApprovedWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza A virus A/Brisbane/02/2018 IVR-190 (H1N1) antigen (propiolactone inactivated)Amaranthus hybridus pollen
go.drugbank.com/drugs/DB15503ApprovedAmaranthus hybridus pollen allergenic extract is used in allergenic testing.
Influenza B virus B/Singapore/INFTT-16-0610/2016 antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB15507ApprovedWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Synonyms: Influenza B virus B/Singapore/INFTT-16-0610/2016 antigen (MDCK cell derived, propiolactone inactivated)