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Displaying results 831 - 840 of 10000 in total
  1. Drug

    Abiraterone

    go.drugbank.com/drugs/DB05812
    ApprovedInvestigational

    Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis

    Synonyms: 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol, (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-olProducts: ABYGA 250 MG TABLET, 120 ADET, ZYTIGA 250 MG TABLET, 120 ADET
  2. Drug

    Pimozide

    go.drugbank.com/drugs/DB01100
    Approved

    A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknow...

    Categories: Heterocyclic Compounds, 2-RingProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 20 ADET
  3. Drug

    Alfacalcidol

    go.drugbank.com/drugs/DB01436
    ApprovedInvestigationalNutraceutical

    Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of [vitamin D]. … Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones.

    Synonyms: (5Z,7E)-9,10-seco-5,7,10(19)-cholestatrien-1α,3β-diol, 9,10-secocholesta-5,7,10(19)-triene-1α,3β-diolProducts: ONE-ALPHA 2 MCG/ML IV AMPUL, 10 ADET, ONE-ALPHA 1 MCG/0.5 ML IV AMPUL, 10 ADET
  4. Drug

    Doxazosin

    go.drugbank.com/drugs/DB00590
    ApprovedInvestigational

    Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension.

    Categories: Heterocyclic Compounds, 2-Ring, Peripheral alpha-1 blockersSynonyms: 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin, 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin
  5. Drug

    Coenzyme M

    go.drugbank.com/drugs/DB09110
    ApprovedInvestigational

    Coenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]

    Synonyms: Coenzym M, Coenzima MProducts: MESNA 100 MG/ML, MEXNAIR 100 MG /ML INYECTABLE
  6. Drug

    Edetate calcium disodium anhydrous

    go.drugbank.com/drugs/DB14598
    ApprovedInvestigational

    [A204173] Edetate calcium disodium was granted FDA approval on 16 July 1953.[L12774]

    Products: LIBENTA AMPUL 2ML, 10 ADET, EDETATO CALCICO DISODICO 20%
  7. Drug

    Mirikizumab

    go.drugbank.com/drugs/DB14910
    ApprovedInvestigational

    It inhibits the actions of interleukin-23 (IL-23), a pro-inflammatory cytokine that activates pathways contributing to the development of inflammatory diseases.

    Categories: Interleukin-23 AntagonistProducts: Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 2 ADET, Misuvya 300 mg/15 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADET
  8. Drug

    Dextran

    go.drugbank.com/drugs/DB09255
    ApprovedInvestigationalVet approved

    [T121] Dextran 40 is a sterile, nonpyrogenic preparation of low molecular weight dextran (average mol. wt. 40,000) in 5% Dextrose Injection or 0.9% Sodium Chloride Injection. … The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units.

    Salts: Dextran 40, Dextran 70Mixtures: Gentran 40 10% Dextrose 5% Inj, LİFE-EXTEND 60 MG/ML DEKSTRAN 70 + 75 MG/ML SODYUM KLORÜR I.V. İNFÜZYON İÇİN ÇÖZELTİ, 250 ML, SETSİZ
  9. Target

    Matrix metalloproteinase-20

    go.drugbank.com/bio_entities/BE0003696
    TargetHumans

    Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role i...

    Polypeptides: Matrix metalloproteinase-20Synonyms: MMP-20
  10. Drug

    Mianserin

    go.drugbank.com/drugs/DB06148
    ApprovedWithdrawn

    A tetracyclic compound with antidepressant effects. Mianserin was previously available internationally, however in most markets it has been phased out in favour of mirtazapine.

    Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepineProducts: MIANSERIN-NEURAX 10 MG, TOLVON TABLET 10 MG, 30 ADET