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Displaying results 831 - 840 of 10000 in total
  1. Target

    DNA gyrase subunit A

    go.drugbank.com/bio_entities/BE0008387
    TargetBacillus subtilis (strain 168)

    A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.

    Polypeptides: DNA gyrase subunit A
  2. Target

    Inhibin beta A chain

    go.drugbank.com/bio_entities/BE0010139
    TargetHumans

    Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid … differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition

    Polypeptides: Inhibin beta A chainSynonyms: Activin beta-A chain
  3. Target

    Human Arylsulfatase A mRNA

    go.drugbank.com/bio_entities/BE0010214
    TargetHumans

  4. Target

    Interleukin-17 receptor A

    go.drugbank.com/bio_entities/BE0018249
    TargetHumans

    Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848) … Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (PubMed:16785495).

    Polypeptides: Interleukin-17 receptor ASynonyms: IL-17 receptor A
  5. Drug

    Interferon alfa-2a

    go.drugbank.com/drugs/DB00034
    ApprovedInvestigationalWithdrawn

    Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. … It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.

    Synonyms: Interferon Alfa 2A, Interferon alfa-2aInternational brands: Roferon A
  6. Drug

    Iron polymaltose

    go.drugbank.com/drugs/DB15763
    ApprovedInvestigationalWithdrawn

    Mixtures: HERREX FOL® JARABE, CHALVER HEMATIN FOL®Synonyms: Iron polymaltose complex, Ferric hydroxide polymaltose complex
  7. Indication

    Chronic Motor and Vocal Tic Disorder

    go.drugbank.com/conditions/DBCOND0082272
    Drugs: Aripiprazole
    Synonyms: Gilles de la Tourette, Gilles de La Tourette's Disease
  8. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300] … Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.

    Mixtures: CHINTA-LAX, BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADETSynonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
  9. Drug

    Haloperidol

    go.drugbank.com/drugs/DB00502
    ApprovedInvestigational

    be caused by a hyperdopaminergic state within the limbic system of the brain. … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one
  10. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    Camphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. … When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity.

    Mixtures: Pain-A-trate Cream, Antiphlogistine Rub A 535 Extra StrengthCategories: Complex Mixtures