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Triethylenetetramine
go.drugbank.com/drugs/DB06824ApprovedInvestigationalTriethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. … [A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and
Categories: Compounds used in a research, industrial, or household settingFasudil
go.drugbank.com/drugs/DB08162InvestigationalFasudil has been investigated in Carotid Stenosis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDisoxaril
go.drugbank.com/drugs/DB08726Experimental5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole is a solid. This compound belongs to the phenol ethers. … These are aromatic compounds containing an ether group substituted with a benzene ring.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-METHYL-5-(7-(P-2-OXAZOLIN-2-YLPHENOXY)HEPTYL)ISOXAZOLE, 5-(7-(4-(4,5-dihydro-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazoleNinvosudil
go.drugbank.com/drugs/DB08756InvestigationalY-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
Categories: Heterocyclic Compounds, 1-RingSynonyms: (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamideNandrolone decanoate
go.drugbank.com/drugs/DB08804ApprovedIllicitInvestigational[A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic … [A233849] Nandrolone decanoate was granted FDA approval on 5 October 1962.[L32564]
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: PARABOLIN RETARD 5 MG AMPUL, 2 ADET, DECA - DURABOLIN® 50 MGLurasidone
go.drugbank.com/drugs/DB08815ApprovedInvestigationalLurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the t...
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: LURAP® 40, LURAP ® 80Tafluprost
go.drugbank.com/drugs/DB08819ApprovedChemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, TAPCOM-S OPHTHALMIC SOLUTIONProducts: SAFLUTAN®, TAFLOTAN-S OPHTHALMIC SOLUTION 0.0015%Temocapril
go.drugbank.com/drugs/DB08836InvestigationalTemocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea. … Temocapril can also be used in hemodialysis patients without risk of serious accumulation.
Categories: Heterocyclic Compounds, 1-RingTesamorelin
go.drugbank.com/drugs/DB08869ApprovedInvestigationalLipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection. … Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients
Synonyms: N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet), GHRH(1-44)