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Displaying results 8441 - 8450 of 10000 in total
  1. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. … Bicuculline is a light-sensitive competitive antagonist of GABAA receptors.

  2. Drug

    Ethylmercurithiosalicylic acid

    go.drugbank.com/drugs/DB02731
    Experimental

    Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.

  3. Drug

    INCB7839

    go.drugbank.com/drugs/DB05033
    Investigational

    It represents a potentially important new class of targeted breast cancer therapy. It has shown promising clinical activity in heavily pretreated, refractory breast cancer patients. … INCB7839 is a novel, orally available ADAM metalloprotease inhibitor that is designed to block activation of the epidermal growth factor (EGFR) pathways.

  4. Drug

    Bimakalim

    go.drugbank.com/drugs/DB19948
    Experimental

    Bimakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Bimakalim is a potassium channel activator, antihypertensive.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Piroximone

    go.drugbank.com/drugs/DB19750
    Experimental

    Piroximone is a small molecule drug. Piroximone has a monoisotopic molecular weight of 217.09 Da.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    NTLA-2001

    go.drugbank.com/drugs/DB18525
    Investigational

    NTLA-2001 is a clustered regularly interspaced short palindromic repeats CRISPR/ Cas9-based gene therapy consisting of a single guide RNA targeting the human TTR gene and a messenger RNA encoding Cas9.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  7. Drug

    Methopterin

    go.drugbank.com/drugs/DB16620
    Investigational

    Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.[A229843]

  8. Drug

    AZD-5423

    go.drugbank.com/drugs/DB12280
    Investigational

    AZD5423 has been used in trials studying the basic science and treatment of Asthma, Bioavailability and AUC, and Chronic Obstructive Pulmonary Disease (COPD).

  9. Drug

    Mebenil

    go.drugbank.com/drugs/DB14728
    Experimental

    An obsolete fungicide used to control various pathogens on cereals and seed potatoes.

    Synonyms: 2-Methyl-N-phenylbenzamide
  10. Drug

    Aloe ferox leaf

    go.drugbank.com/drugs/DB14257
    Approved

    Aloe ferox leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.