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Celecoxib
go.drugbank.com/drugs/DB00482ApprovedInvestigationalCelecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other … [L7604] Interestingly, selective COX-2 inhibitors (especially celecoxib), have been evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of malignancies
Categories: Cyclooxygenase-2 (COX-2) Inhibitors, COX-2 InhibitorsSynonyms: p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamideBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … [A179002] Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than [clonidine] or [apraclonidine], which are also alpha-2 adrenergic agonists.
Mixtures: NEFRIDAXEM B+D, Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4%Categories: Heterocyclic Compounds, 2-Ring, Adrenergic alpha-2 Receptor AgonistsMiglitol
go.drugbank.com/drugs/DB00491ApprovedMiglitol should be taken at the start of a meal for maximal effect and the effect will depend on the amount of poly and oligosaccharides in the diet. … It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into
Categories: Heterocyclic Compounds, 1-RingCefotaxime
go.drugbank.com/drugs/DB00493ApprovedInvestigationalCefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria.
Mixtures: SEFOTAK 1 G IM ENJEKSİYONLUK TOZ İÇEREN FLAKON, 1 ADETCategories: Heterocyclic Compounds, 2-RingPhenindione
go.drugbank.com/drugs/DB00498ApprovedInvestigationalAn indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th e...
Synonyms: 2-Phenyl-1,3-indandione, 2-phenyl-1,3-diketohydrindeneCategories: Vitamin K AntagonistsTolmetin
go.drugbank.com/drugs/DB00500ApprovedA non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-5-p-toluoylpyrrole-2-acetic acid, 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acidCimetidine
go.drugbank.com/drugs/DB00501ApprovedInvestigationalA histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Mixtures: Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17%, Cimetidine 10% / Lidocaine 5% / Salicylic Acid 40%Categories: MATE 1 Inhibitors, MATE 1 SubstratesLevallorphan
go.drugbank.com/drugs/DB00504ApprovedAn opioid antagonist with properties similar to those of naloxone; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate...
Categories: Heterocyclic Compounds with 4 or More RingsCarteolol
go.drugbank.com/drugs/DB00521ApprovedA beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 ML, CARTEOL LP %2 UZUN ETKILI GOZ DAMLASI, 3 MLBentiromide
go.drugbank.com/drugs/DB00522ApprovedWithdrawnBentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy.
Categories: Compounds used in a research, industrial, or household setting