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Displaying results 841 - 850 of 9667 in total
  1. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Products: Loniten 10mg, VAXDIL® TABLETAS 10MG
  2. Drug

    Mesalazine

    go.drugbank.com/drugs/DB00244
    ApprovedInvestigational

    Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent

    Products: ASACOL 400MG, SALOFALK 250MG
  3. Drug

    Melphalan

    go.drugbank.com/drugs/DB01042
    ApprovedInvestigational

    [L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard. … [L40928] It is also used for high-conditioning before hematopoietic stem cell transplant.[L47890] It is also used to treat uveal melanoma with unresectable hepatic metastases.[L47895]

    Synonyms: L-PAMProducts: Alkeran Injection 50mg, MYELKILAN® 50MG POLVO PARA INYECCIÓN
  4. Drug

    Histidine

    go.drugbank.com/drugs/DB00117
    ApprovedInvestigationalNutraceutical

    An essential amino acid that is required for the production of histamine.

    Mixtures: LEVAMIN PAD, EAS ORAL 100 TABLETProducts: CAREDO Treating Periodontitis Toothpastes 100g
  5. Drug

    Halofantrine

    go.drugbank.com/drugs/DB01218
    ApprovedWithdrawn

    Halofantrine has been shown to preferentially block open and inactivated HERG channels leading to some degree of cardiotoxicity. … It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine.

    Products: Halfan - Tab 250mg
  6. Drug

    Metocurine iodide

    go.drugbank.com/drugs/DB00416
    ApprovedWithdrawn

    It is used as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy Metocurine iodide has a moderate risk of inducing histamine … release and has some ganglion blocking activity.

    Products: Metubine Iodide Inj 2mg/ml
  7. Drug

    Nelfinavir

    go.drugbank.com/drugs/DB00220
    ApprovedInvestigational

    It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.

    Products: Viracept -50mg, Viracept -250mg
  8. Drug

    Remdesivir

    go.drugbank.com/drugs/DB14761
    ApprovedInvestigational

    [A191379, A222393] Broad antiviral activity of remdesivir is suggested by its mechanism of action,[A222398] and to date, it has demonstrated _in vitro_ activity against the _Arenaviridae_, _Flaviviridae … [A191427, A198810] Remdesivir was confirmed as a non-obligate chain terminator of RdRp from SARS-CoV-2 and the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical

    Products: COVIFOR (REMDESIVIR FOR INJECTION 100MG/VIAL), VEKLURY® LYOPHILIZED POWDER FOR IV INFUSION 100MG/VIAL
  9. Drug

    Fenofibric acid

    go.drugbank.com/drugs/DB13873
    ApprovedInvestigational

    It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol. … [A32038,L12855] Due to its high hydrophilicity and poor absorption profile,[A32038] prodrug ,[fenofibrate], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed

    Products: Trilipix Modified Release Capsules 45mg
  10. Drug

    Doconexent

    go.drugbank.com/drugs/DB03756
    ApprovedInvestigational

    A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. … It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae.

    Mixtures: Live-well™ Toco-E CapsuleProducts: Nova Neurogel DHA 250mg Softgel Capsule