Search

Displaying results 841 - 850 of 1993 in total
  1. Target

    Leukotriene B4 receptor 2

    go.drugbank.com/bio_entities/BE0003489
    TargetHumans

    Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages.

    Polypeptides: Leukotriene B4 receptor 2Synonyms: LTB4 receptor JULF2, Leukotriene B4 receptor BLT2
  2. Target

    Nuclear receptor coactivator 2

    go.drugbank.com/bio_entities/BE0003740
    TargetHumans

    Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3 (PubMed:23508108).

    Polypeptides: Nuclear receptor coactivator 2Function: aryl hydrocarbon receptor binding
  3. Target

    Thyroid hormone receptor alpha

    go.drugbank.com/bio_entities/BE0003867
    TargetHumans

    Polypeptides: Thyroid hormone receptor alphaSynonyms: Nuclear receptor subfamily 1 group A member 1, Thyroid hormone receptor, alpha isoform 1 variant
  4. Target

    Nuclear receptor coactivator 5

    go.drugbank.com/bio_entities/BE0004057
    TargetHumans

    Nuclear receptor coregulator that can have both coactivator and corepressor functions. … Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2.

    Polypeptides: Nuclear receptor coactivator 5
  5. Target

    receptor protein-tyrosine kinase

    go.drugbank.com/bio_entities/BE0004155
    TargetHumans

    Polypeptides: receptor protein-tyrosine kinaseSynonyms: Met proto-oncogene variant
  6. Target

    Acetylcholine receptor subunit alpha

    go.drugbank.com/bio_entities/BE0004661
    TargetHumans

    Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane

    Polypeptides: Acetylcholine receptor subunit alpha
  7. Target

    Hyaluronan mediated motility receptor

    go.drugbank.com/bio_entities/BE0004702
    TargetHumans

    Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs.

    Polypeptides: Hyaluronan mediated motility receptorSynonyms: Receptor for hyaluronan-mediated motility
  8. Target

    Orexin receptor type 2

    go.drugbank.com/bio_entities/BE0005865
    TargetHumans

    G protein-coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin (PubMed:26950369, PubMed:33547286, PubMed:35614071, PubMed:9491897

    Polypeptides: Orexin receptor type 2Synonyms: Hypocretin receptor type 2
  9. Target

    Sulfonylurea receptor 1, Kir6.2

    go.drugbank.com/bio_entities/BE0008670
    TargetHumans

    Regulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11; KCNJ11 forms the channel pore while ABCC8 is requ...

    Synonyms: Sulfonylurea receptor 1
  10. Target

    Transferrin receptor protein 1

    go.drugbank.com/bio_entities/BE0008725
    TargetHumans

    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738, PubMed:41772062). … The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.

    Polypeptides: Transferrin receptor protein 1Synonyms: Transferrin receptor 1