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Pseudoephedrine
go.drugbank.com/drugs/DB00852ApprovedPseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system. … [A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823]
Mixtures: Entex T, Pediatex TDCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Adrenergic alpha-1 Receptor AgonistsCariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigationalCariprazine gained its first global approval in the US in September 2015 [A3941] and was later approved by Health Canada in April 2022. … [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes associated with bipolar I disorder.[L41655,L40198]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor AgonistsPepsin
go.drugbank.com/drugs/DB13198ApprovedWithdrawnInterestingly, recent research has suggested that pepsin participates in the digestion of nucleic acids [L2391]. … Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated egg whites to dissolve.
Zinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalZinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". … It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Mixtures: Micro+ Te Pediatric, M T E 4 Concentrate InjProducts: SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE.Evinacumab
go.drugbank.com/drugs/DB15354ApprovedInvestigationalThe ANGPTL family of proteins serve a number of physiologic functions - including involvement in the regulation of lipid metabolism - which have made them desirable therapeutic targets in recent years. … (HoFH) under the brand name "Evkeeza".
Niacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Mixtures: Folika-T, TL-FluoriviteSulisobenzone
go.drugbank.com/drugs/DB11185ApprovedSulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38]. … It works to filter out both UVA and UVB rays, protecting the skin from sun UV damage [L2153].
Mixtures: Rayito de Sol, Rayito de SolZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalThis drug decreases the time to fall asleep (sleep latency), increases the duration of sleep, and decreases the number of awakenings during sleep in patients with temporary (transient) insomnia. … This drug has the propensity to completely or partially reverse the abnormal metabolism of damaged brain cells after injury [L5584], [A175444].
Categories: GABA-A Receptor Agonists, gamma-Aminobutyric Acid A Receptor Positive ModulatorProducts: Zoldem 5 mg - Filmtabletten, Zoldem 10 mg - FilmtablettenFerrous sulfate anhydrous
go.drugbank.com/drugs/DB13257ApprovedInvestigational[A190528] Ferrous sulfate is a synthetic agent used in the treatment of iron deficiency. It is the gold standard of oral iron therapy in the UK and many other countries.[L2234,L2246] … [A190804] This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells.
International brands: Fe-PlusMixtures: TL-Fol 500, Quflora FE Pediatric DropsPhenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalIt promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
Mixtures: Re-PB Hyos, Re-PB Hyos