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Elapegademase
go.drugbank.com/drugs/DB14712Approved[F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on October 5, 2018.[L4654,F1939]
Plozasiran
go.drugbank.com/drugs/DB18997ApprovedInvestigational[L45864] Plozasiran was first approved by the FDA on November 18th, 2025, to reduce triglycerides in Adults with Familial Chylomicronemia Syndrome (FCS).[L54603]
Carbamazepine
go.drugbank.com/drugs/DB00564ApprovedInvestigationalIt was initially approved by the FDA in 1965.[A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1.
Norgestimate
go.drugbank.com/drugs/DB00957ApprovedInvestigational[L11845,L11848] Norgestimate was granted FDA approval on 29 December 1989.[L11842]
Pindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigational[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Ganirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigational[A252195] Ganirelix was first approved by the FDA on July 29, 1999.[L43070]
Perampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalThe FDA label includes an important black-boxed warning of serious or life-threatening behavioral and psychiatric reactions in patients taking Fycompa™.
Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018. … [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with [remdesivir] under the Emergency Use Authorization (EUA) in November 2020,[L22619] the FDA fully approved
Anatibant
go.drugbank.com/drugs/DB05038ExperimentalAnatibant is a selective, very potent, small-molecule Bradykinin B2 receptor antagonist. It is developed for the for the treatment of traumatic brain injury (TBI).
Oxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigational[Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]