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Milpecitinib
go.drugbank.com/drugs/DB21676ExperimentalMilpecitinib is a small molecule drug. Milpecitinib has a monoisotopic molecular weight of 380.13 Da.
Claziprotamide
go.drugbank.com/drugs/DB21687ExperimentalClaziprotamide is a small molecule drug. Claziprotamide has a monoisotopic molecular weight of 374.13 Da.
Valinomycin
go.drugbank.com/drugs/DB14057Experimental(From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies. … It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: Potassium ionophore IErythroxylum catuaba bark
go.drugbank.com/drugs/DB14300Investigational"Catuaba" is a general term for a medicinal infusion created by the bark of plants belonging to the _Erythroxylum_ genus, though this name is also applied to infusions of plants belonging to other genera … [A215262] The infusion is thought to carry stimulant and aphrodisiac effects,[A215262] and catuaba made specifically with _Trichilia catigua_ has been investigated for use in depression.[A215267]
N,N-dimethylarginine
go.drugbank.com/drugs/DB01686ExperimentalIt is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid. … Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma.
Synonyms: N(G),N(G)-Dimethylarginine, N(5)-((Dimethylamino)iminomethyl)-L-ornithine3'-phospho-5'-adenylyl sulfate
go.drugbank.com/drugs/DB02902Experimental3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate … It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process of sulfur fixation in plants and microorganisms.
Synonyms: 3'-phospho-5'-adenylyl sulfate, 3'-phosphoadenosine 5'-phosphosulfateOditrasertib
go.drugbank.com/drugs/DB21526InvestigationalOditrasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Oditrasertib is a serine/threonine kinase inhibitor. … Oditrasertib is under investigation in clinical trial NCT05630547 (A Study to Evaluate the Effect of SAR443820 on Serum Neurofilament Levels in Male and Female Adult Participants With Multiple Sclerosis
Ruserontinib
go.drugbank.com/drugs/DB21555InvestigationalRuserontinib is under investigation in clinical trial NCT04716114 (A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated). … Ruserontinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor.
Categories: Heterocyclic Compounds, 2-RingVociprotafib
go.drugbank.com/drugs/DB21559InvestigationalVociprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Vociprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor. … Vociprotafib has a monoisotopic molecular weight of 450.16 Da.
Enbezotinib
go.drugbank.com/drugs/DB21565InvestigationalEnbezotinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Enbezotinib is a tyrosine kinase inhibitor. … Enbezotinib is under investigation in clinical trial NCT04161391 (Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations).