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Filapixant
go.drugbank.com/drugs/DB21467ExperimentalFilapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight of 521.17 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesEnclomiphene
go.drugbank.com/drugs/DB06735InvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesGinsenoside C
go.drugbank.com/drugs/DB06748ExperimentalNutraceuticalCategories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 Enzyme InhibitorsPinacidil
go.drugbank.com/drugs/DB06762ApprovedPinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood press...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTasosartan
go.drugbank.com/drugs/DB01349ExperimentalTasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAprindine
go.drugbank.com/drugs/DB01429ExperimentalAprindine is a cardiac depressant used in arrhythmias.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesDesomorphine
go.drugbank.com/drugs/DB01531ExperimentalIllicitCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesMethylenedioxyethamphetamine
go.drugbank.com/drugs/DB01566ExperimentalIllicitCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCholesterol
go.drugbank.com/drugs/DB04540ApprovedInvestigationalWithdrawnThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Categories: P-glycoprotein inhibitorsPrenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates