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Displaying results 8571 - 8580 of 10000 in total
  1. Drug

    Demeclocycline

    go.drugbank.com/drugs/DB00618
    Approved

    A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.

    Synonyms: 6-demethyl-7-chlorotetracycline, 7-chloro-6-demethyltetracycline
  2. Drug

    Oxandrolone

    go.drugbank.com/drugs/DB00621
    ApprovedInvestigational

    A synthetic hormone with anabolic and androgenic properties.

    Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  3. Drug

    Guanabenz

    go.drugbank.com/drugs/DB00629
    ApprovedWithdrawn

    Guanabenz is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

    Synonyms: N-(2,6-DICHLOROBENZYLIDENE)-N'-AMIDINOHYDRAZINE, 2-((2,6-DICHLOROPHENYL)METHYLENE)HYDRAZINECARBOXIMIDAMIDECategories: Cytochrome P-450 Substrates, Adrenergic alpha-2 Receptor Agonists
  4. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].

    Synonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acidMixtures: ALENDRON-HEXAL 4 WO CAL D, BONEX-D 70 MG / 2800 IU TABLET, 4 ADET
  5. Drug

    Astemizole

    go.drugbank.com/drugs/DB00637
    ApprovedWithdrawn

    Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms.

    Synonyms: 1-(p-Fluorobenzyl)-2-((1-(2-(p-methoxyphenyl)ethyl)piperid-4-yl)amino)benzimidazole, 1-(p-Fluorobenzyl)-2-((1-(p-methoxyphenethyl)-4-piperidyl)amino)benzimidazoleCategories: Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  6. Drug

    Mebendazole

    go.drugbank.com/drugs/DB00643
    ApprovedInvestigationalVet approved

    A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]

    Synonyms: (5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl esterMixtures: L-OMBRIX-DUET, L-OMBRIX-DUET
  7. Drug

    Dextropropoxyphene

    go.drugbank.com/drugs/DB00647
    ApprovedIllicitWithdrawn

    The drug is often referred to as the general form, "propoxyphene", however only the dextro-isomer (dextropropoxyphene) has any analgesic effect. … The levo-isomer appears to exhibit a very limited antitussive effect.

    Synonyms: d-PropoxypheneMixtures: Darvocet-N 50, Darvocet-N 100
  8. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. … It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione.

    Synonyms: 3-Hydroxy-1,3,5(10)-estratrien-17-oneCategories: P-glycoprotein inducers, Cytochrome P-450 Substrates
  9. Drug

    Sulfametopyrazine

    go.drugbank.com/drugs/DB00664
    ApprovedWithdrawn

    Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.

  10. Drug

    Nilutamide

    go.drugbank.com/drugs/DB00665
    ApprovedInvestigational

    Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). … Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer.

    Synonyms: 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoinCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring