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Tauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.
Products: TAUROLITE 250 MG 100 KAPSULBezafibrate
go.drugbank.com/drugs/DB01393ApprovedInvestigationalAntilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsSynonyms: 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acidY+L amino acid transporter 2
go.drugbank.com/bio_entities/BE0009872TransporterHumansHeterodimer with SLC3A2, that functions as an antiporter which operates as an efflux route by exporting cationic amino acids such as L-arginine from inside the cells in exchange with neutral amino acids like L-leucine, L-glutamine and is...
Polypeptides: Y+L amino acid transporter 2Synonyms: Y+LAT2, y+LAT-2Neuropeptide Y receptor type 4-2
go.drugbank.com/bio_entities/BE0024014TargetHumansG protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP.
Polypeptides: Neuropeptide Y receptor type 4-2Alogliptin
go.drugbank.com/drugs/DB06203ApprovedInvestigationalFDA approved January 25, 2013. … Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4).
Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAtosiban
go.drugbank.com/drugs/DB09059ApprovedInvestigationalAtobisan was developed by the Swedish company Ferring Pharmaceuticals. It was first reported in the literature in 1985. … Although initial studies suggested it could be used as a nasal spray and hence would not require hospital admission, it is not used in that form.
Categories: Genito Urinary System and Sex HormonesProducts: EVERPREM® SOLUCIÓN PARA INFUSIÓN 6.75 MG/0.9 ML, TRACTOCILE 37.5 MG/ 5 ML CONCENTRADO PARA SOLUCION POR INFUSIONNilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalNilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). … ), another tyrosine kinase inhibitor used as a first-line treatment for CML.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesProducts: TASIGNA® 150 MG CAPSULAS, TASIGNA (200 MG)Nitrendipine
go.drugbank.com/drugs/DB01054ApprovedWithdrawnNitrendipine is a calcium channel blocker with marked vasodilator action.
Mixtures: ENEAS® 10/20 MG COMPRIMIDOS, ENEAS® 10/20 MG COMPRIMIDOSCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEntecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalIt was approved by the U.S. Food and Drug Administration (FDA) in March 2005. … Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: HEPATOVIR-B 0.05 MG/ML ORAL ÇÖZELTİ, 210 ML, HEPAGARD 0.05 MG/ML ORAL ÇÖZELTI ,240 MLPivampicillin
go.drugbank.com/drugs/DB01604ApprovedWithdrawnPivalate ester analog of ampicillin.
Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: PIVACIL KAPSUL 350 MG, 500 ADET, PIVACIL KAPSUL 350 MG, 1000 ADET