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Cefditoren
go.drugbank.com/drugs/DB01066ApprovedCefditoren is an oral third-generation cephalosporin. It is commonly marketed under the trade name Spectracef by Cornerstone BioPharma.
Categories: Heterocyclic Compounds, 2-RingProducts: MEIACT MS FINE GRANULES 10%Promethazine
go.drugbank.com/drugs/DB01069ApprovedInvestigationalPromethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of [phenothiazine] that was developed in France in 1946. … [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.
Synonyms: (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine, N-(2'-dimethylamino-2'-methyl)ethylphenothiazineMixtures: SP-CODRINE SYRUP, SP-COSEDYL SYRUPDihydrotachysterol
go.drugbank.com/drugs/DB01070ApprovedWithdrawnA vitamin D that can be regarded as a reduction product of vitamin D2.
Categories: Vitamin D and AnaloguesEtidronic acid
go.drugbank.com/drugs/DB01077ApprovedInvestigationalEtidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid]. … [A203111] Etidronic acid was granted FDA approval on 1 September 1977.[L13901]
Synonyms: 1-Hydroxy-1,1-diphosphonoethane, (1-Hydroxyethylene)diphosphonic acidTegaserod
go.drugbank.com/drugs/DB01079ApprovedWithdrawnmechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal wall to facilitate actions like esophageal relaxation, peristaltic gut movement, and … in female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular event than the broader population.
Synonyms: 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidineCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesStreptomycin
go.drugbank.com/drugs/DB01082ApprovedInvestigationalVet approved[A233325,A232294] Although streptomycin was the first antibiotic determined to be effective against mycobacterium tuberculosis, it has fallen out of favor due to resistance and is now primarily used as
Synonyms: 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranosideCategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexOrlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalThe global prevalence of obesity is increasing rapidly. … [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: SLENDER 1, LINADEX®Emedastine
go.drugbank.com/drugs/DB01084ApprovedEmedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Synonyms: 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole, 1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazoleCategories: Heterocyclic Compounds, 2-RingDeserpidine
go.drugbank.com/drugs/DB01089ApprovedWithdrawnDeserpidine is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive properties that has been used for the control of high blood pressure
Categories: Heterocyclic Compounds, 2-RingPentolinium
go.drugbank.com/drugs/DB01090ApprovedPentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.
Categories: Heterocyclic Compounds, 1-Ring