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Cilobradine
go.drugbank.com/drugs/DB20039InvestigationalCilobradine is under investigation in clinical trial NCT02264041 (Effect of Cytochrome P 450 3A4 Inhibition by Itraconazole on the Single Oral Dose Pharmacokinetics of Cilobradine).
Nafimidone
go.drugbank.com/drugs/DB20780ExperimentalNafimidone is a small molecule drug. Nafimidone has a monoisotopic molecular weight of 236.09 Da.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2D6 InhibitorsFantofarone
go.drugbank.com/drugs/DB20875ExperimentalFantofarone is a small molecule drug. Fantofarone has a monoisotopic molecular weight of 550.25 Da.
Categories: P-glycoprotein inhibitorsOxeclosporin
go.drugbank.com/drugs/DB21134ExperimentalOxeclosporin is a small molecule drug. The usage of the INN stem '-(clo)sporin' in the name indicates that Oxeclosporin is a cyclosporine derivative. Oxeclosporin has a monoisotopic molecular weight of 1261.86 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBefetupitant
go.drugbank.com/drugs/DB21149ExperimentalThe usage of the INN stem '-pitant' in the name indicates that Befetupitant is a neurokinin NK1 (substance P) receptor antagonist. Befetupitant has a monoisotopic molecular weight of 565.22 Da.
Fosrolapitant
go.drugbank.com/drugs/DB21723InvestigationalThe usage of the INN stem '-pitant' in the name indicates that Fosrolapitant is a neurokinin NK1 (substance P) receptor antagonist. Fosrolapitant has a monoisotopic molecular weight of 654.16 Da.
Fenbendazole
go.drugbank.com/drugs/DB11410InvestigationalVet approvedFenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, ae...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesMirodenafil
go.drugbank.com/drugs/DB11792InvestigationalMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCarboxyamidotriazole
go.drugbank.com/drugs/DB11960InvestigationalCarboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGDC-0623
go.drugbank.com/drugs/DB11982InvestigationalGDC-0623 has been used in trials studying the treatment of Solid Cancers.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates