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Displaying results 861 - 870 of 10000 in total
  1. Target

    Apolipoprotein B-100

    go.drugbank.com/bio_entities/BE0009908
    TargetHumans

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). … Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor

    Polypeptides: Apolipoprotein B-100Synonyms: Apo B-100
  2. Drug

    Hydrotalcite

    go.drugbank.com/drugs/DB13322
    ApprovedInvestigationalWithdrawn

    Products: HIDRASIT 1000 MG ÇİĞNEME TABLET, 24 ADET, JASIVENTER 500 MG
  3. Drug

    Selegiline

    go.drugbank.com/drugs/DB01037
    ApprovedInvestigationalVet approved

    A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may...

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 SubstratesProducts: MOVERDIN 5 MG TABLET, 100 ADET, SELEGILIN-NEURAX 10 MG
  4. Drug

    Pimozide

    go.drugbank.com/drugs/DB01100
    Approved

    A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 500 ADET
  5. Drug

    Anvatabart opadotin

    go.drugbank.com/drugs/DB18290
    Investigational

    Synonyms: gamma1 heavy chain humanized (1-449) [VH humanized (Homo sapiens IGHV3-66*01 (81.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01, G1m17,1 (CH1 A1.4>, kappa, anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody; conjugated at two
  6. Drug

    Candesartan cilexetil

    go.drugbank.com/drugs/DB00796
    ApprovedInvestigational

    Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents … Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension.

    Mixtures: CANDAM® 10/16 MG TABLETAS, CANDAM® 10/16 MG TABLETASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  7. Drug

    Arformoterol

    go.drugbank.com/drugs/DB01274
    Approved

    It works by relaxing muscles in the airways to improve breathing. … The use of arformoterol is pending revision due to safety concerns in regards to an increased risk of severe exacerbation of asthma symptoms, leading to hospitalization as well as death in some patients

    Mixtures: AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 60 KPS, AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 120 KPSCategories: Agents to Treat Airway Disease, Cytochrome P-450 Substrates
  8. Drug

    Diosmin

    go.drugbank.com/drugs/DB08995
    ApprovedInvestigational

    Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.

    Mixtures: DIOKERN 450 MG/50 MG FILM KAPLI TABLET,60 ADET, VARIDOS 450 MG/50 MG FILM KAPLI TABLET, 60 ADETCategories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 CYP2E1 Inhibitors
  9. Drug

    Abatacept

    go.drugbank.com/drugs/DB01281
    ApprovedInvestigational

    [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each … Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human

    Categories: Selective T Cell Costimulation ModulatorProducts: ORENCIA 250 MG KON.PERFUZYONLUK COZ.ICIN TOZ ICEREN FLAKON, ORENCIA® 250 MG - POLVO LIOFILIZADO PARA SOLUCIÓN INYECTABLE INTRAVENOSA
  10. Drug

    Econazole

    go.drugbank.com/drugs/DB01127
    Approved

    A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.

    Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: Pevaryl 10 mg/g Creme, Gyno-Pevaryl 10 mg/g Vaginalcreme