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Displaying results 861 - 870 of 10000 in total
  1. Drug

    Oxytocin

    go.drugbank.com/drugs/DB00107
    ApprovedInvestigationalVet approved

    Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. … [A229013] Oxytocin also serves a role in metabolic homeostasis and cardiovascular regulation.[A228593,A229098]

    Mixtures: Bakumokon 5% Minoxidil, Bakumokon 7% Minoxidil SulfateProducts: OKSİTOSEL 5 IU/ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 3 ADET, Oxytocin Grindeks 5 I.E./ml Injektions-/Infusionslösung
  2. Drug

    Ethinylestradiol

    go.drugbank.com/drugs/DB00977
    ApprovedInvestigational

    [A191107] Ethinylestradiol was granted FDA approval on 25 June 1943.[L11884] … Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering.[A191107] It was developed in an effort to create an estrogen with greater oral bioavailability.

    Mixtures: GINERA 75 MCG/30 MCG KAPLI TABLET, 21 ADET, SECRET 25Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    Finasteride

    go.drugbank.com/drugs/DB01216
    ApprovedInvestigational

    It works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone

    Mixtures: Finasteride 0.1% / Minoxidil 5%, Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5%Categories: 5-alpha Reductase Inhibitors, Drugs Used in Benign Prostatic Hypertrophy
  4. Drug

    Fluocortolone

    go.drugbank.com/drugs/DB08971
    ApprovedWithdrawn

    Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.

    Mixtures: SCHERIPROCT N CREAM, ULTRALAN POMAT, 20 GRCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  5. Drug

    Amiloride

    go.drugbank.com/drugs/DB00594
    ApprovedInvestigational

    A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. … This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct.

    Mixtures: Nu-amilzide 5/50 Mg Tab, Riva-amilzide 5/50 mgCategories: Decreased Renal K+ Excretion, Heterocyclic Compounds, 1-Ring
  6. Drug

    Mepivacaine

    go.drugbank.com/drugs/DB00961
    ApprovedInvestigationalVet approved

    Mepivacaine is effective topically only in large doses and therefore should not be used by this route. (From AMA Drug Evaluations, 1994, p168) … A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia.

    Mixtures: Scandonest 2% L, ODONTOCAINA ® 2%Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Estradiol valerate

    go.drugbank.com/drugs/DB13956
    ApprovedInvestigationalVet approved

    The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 70 to 500 mcg of estradiol daily, depending on the phase of the menstrual cycle. … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).

    Mixtures: DIVICONT TABLETAS 1 MG/5 MG, MESIGYNA 5 MG+50 MG/1 ML ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTÖRCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  8. Drug

    Butamirate

    go.drugbank.com/drugs/DB13731
    Investigational

    Products: TUSAMOL 7,5 MG/5 ML SURUP, CODACTIV 7,5 MG/5 ML SURUP, 100 ML
  9. Drug

    Naratriptan

    go.drugbank.com/drugs/DB00952
    Approved

    Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.

    Synonyms: N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide, N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamideCategories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor Agonists
  10. Drug

    Chlorpropamide

    go.drugbank.com/drugs/DB00672
    ApprovedWithdrawn

    Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites.

    Synonyms: N-(4-chlorophenylsulfonyl)-N'-propylurea, N-(p-chlorobenzenesulfonyl)-N'-propylureaCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates