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Displaying results 8751 - 8760 of 10000 in total
  1. Drug

    Vortioxetine

    go.drugbank.com/drugs/DB09068
    ApprovedInvestigational

    receptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. … It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: KELAC 5 MG, KELAC® 10MG
  2. Drug

    Trimetazidine

    go.drugbank.com/drugs/DB09069
    ApprovedInvestigational

    [L33015] Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s. … [A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate

    Synonyms: 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochlorideCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Lenvatinib

    go.drugbank.com/drugs/DB09078
    ApprovedInvestigational

    3, and 4; the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET. … In particular, VEGF has been identified as a crucial regulator of both physiologic and pathologic angiogenesis and increased expression of VEGF is associated with a poor prognosis in many types of cancers

    Synonyms: 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamideCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  4. Drug

    Vilanterol

    go.drugbank.com/drugs/DB09082
    ApprovedInvestigational

    with the (R)-configuration. … Vilanterol is a selective long-acting β2-adrenergic agonist (LABA) with inherent 24-hour activity for the once-daily treatment of COPD and asthma.

    Mixtures: RELVAR® ELLIPTA® 100MCG/25MCG, RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓNCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  5. Drug

    Tetracaine

    go.drugbank.com/drugs/DB09085
    ApprovedInvestigationalVet approved

    Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

    Synonyms: 2-(dimethylamino)ethyl 4-(butylamino)benzoate, 2-(Dimethylamino)ethyl p-(butylamino)benzoateMixtures: Lidocaine 7% / Tetracaine 7%, Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%.
  6. Drug

    Eugenol

    go.drugbank.com/drugs/DB09086
    ApprovedInvestigational

    It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. … Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    Daclatasvir

    go.drugbank.com/drugs/DB09102
    ApprovedInvestigationalWithdrawn

    Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. … Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV).

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: I-HEP CLASTAVIR 30, I-HEP CLASTAVIR 60
  8. Drug

    Calcium carbimide

    go.drugbank.com/drugs/DB09116
    ApprovedWithdrawn

    Calcium carbimide, sold as the citrate salt, is an alcohol-sensitizing agent. … Calcium carbimide was conceived as an alternative for the treatment of alcoholism with a reduced side effect profile either when it is consumed accompanied by alcohol or without it.

    Synonyms: Cyanamide, calcium salt (1:1), methanediimine, calcium salt (1:1)
  9. Drug

    Potassium citrate

    go.drugbank.com/drugs/DB09125
    ApprovedInvestigationalVet approved

    Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. … In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis.

    Mixtures: B 6 Plus, Formula No. 2 Plus K LiqProducts: Urocit-K, Polycitra-K
  10. Drug

    Iothalamic acid

    go.drugbank.com/drugs/DB09133
    Approved

    Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.

    Synonyms: 1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamateSalts: Iothalamate sodium I-125