Search

Displaying results 8771 - 8780 of 10000 in total
  1. Target

    Flavin-containing monooxygenase 3

    go.drugbank.com/bio_entities/BE0003606
    EnzymeHumans

    Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds (PubMed:10759686, PubMed:30381441, PubMed:32156684). Plays an important r...

    Polypeptides: Flavin-containing monooxygenase 3Synonyms: FMO form 2, FMO 3
  2. Target

    Organic anion transporter 3

    go.drugbank.com/bio_entities/BE0003645
    TargetTransporterEnzymeHumans

    Contributes to the renal uptake of potent uremic toxins (indoxyl sulfate (IS), indole acetate (IA), hippurate/N-benzoylglycine (HA) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF)), pravastatin … Transports organic anions such as estrone 3-sulfate (E1S) and urate in exchange for dicarboxylates such as glutarate or ketoglutarate (2-oxoglutarate) (PubMed:14586168, PubMed:15846473, PubMed:15864504

    Polypeptides: Organic anion transporter 3
  3. Target

    Rhoptry neck protein 3

    go.drugbank.com/bio_entities/BE0009222
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Rhoptry neck protein 3Synonyms: Rhoptry neck protein 3, putative
  4. Target

    Equilibrative nucleoside transporter 3

    go.drugbank.com/bio_entities/BE0010035
    TransporterHumans

    Uniporter that mediates the facilitative transport of nucleoside across lysosomal and mitochondrial membranes (PubMed:15701636, PubMed:19164483, PubMed:20595384, PubMed:28729424). Functions as a non-electrogenic Na(+)-independent transpo...

    Polypeptides: Equilibrative nucleoside transporter 3Synonyms: Solute carrier family 29 member 3
  5. Target

    Melanoma-associated antigen 3

    go.drugbank.com/bio_entities/BE0010446
    TargetHumans

    Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a repressor of autophagy (PubMed:20864041, PubMed:31267705). May enhance ubiquitin ligase activity of TRIM28 and stimula...

    Polypeptides: Melanoma-associated antigen 3Synonyms: MAGE-3 antigen
  6. Target

    Delta-like protein 3

    go.drugbank.com/bio_entities/BE0010784
    TargetHumans

    Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity)

    Polypeptides: Delta-like protein 3Synonyms: Drosophila Delta homolog 3
  7. Target

    Bombesin receptor subtype-3

    go.drugbank.com/bio_entities/BE0013148
    TargetHumans

    Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system

    Polypeptides: Bombesin receptor subtype-3Synonyms: BRS-3
  8. Pathway

    De Novo Triacylglycerol Biosynthesis TG(20:3(5Z,8Z,11Z)/18:2(9Z,12Z)/18:3(6Z,9Z,12Z))

    smpdb.ca/view/SMP0023223
    Metabolic

    The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha, Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
  9. Pathway

    De Novo Triacylglycerol Biosynthesis TG(20:3(5Z,8Z,11Z)/18:3(9Z,12Z,15Z)/18:2(9Z,12Z))

    smpdb.ca/view/SMP0023312
    Metabolic

    The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha, Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
  10. Pathway

    De Novo Triacylglycerol Biosynthesis TG(18:2(9Z,12Z)/20:3(5Z,8Z,11Z)/18:3(9Z,12Z,15Z))

    smpdb.ca/view/SMP0024259
    Metabolic

    The enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the glycerol backbone … Second, the mitochondrial outer membrane enzyme glycerol-3-phosphate acyltransferase esterifies an acyl-group to the sn-1 position of sn-glycerol 3-phosphate to form 1-acyl-sn-glycerol 3-phosphate (lysophosphatidic

    Drugs: NADH · sn-glycerol 3-phosphate · Dihydroxyacetone phosphate
    Enzymes: 1-Acyl-sn-glycerol-3-phosphate acyltransferase alpha, Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic