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Displaying results 8781 - 8790 of 10000 in total
  1. Drug

    Trimetazidine

    go.drugbank.com/drugs/DB09069
    ApprovedInvestigational

    [L33015] Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s. … [A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[2,3,4-trimethoxybenzyl] piperazine dihydrochloride
  2. Drug

    Lenvatinib

    go.drugbank.com/drugs/DB09078
    ApprovedInvestigational

    3, and 4; the platelet derived growth factor receptor alpha (PDGFRα), KIT, and RET. … In particular, VEGF has been identified as a crucial regulator of both physiologic and pathologic angiogenesis and increased expression of VEGF is associated with a poor prognosis in many types of cancers

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide
  3. Drug

    Vilanterol

    go.drugbank.com/drugs/DB09082
    ApprovedInvestigational

    with the (R)-configuration. … Vilanterol is a selective long-acting β2-adrenergic agonist (LABA) with inherent 24-hour activity for the once-daily treatment of COPD and asthma.

    Mixtures: RELVAR® ELLIPTA® 100MCG/25MCG, RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓNCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  4. Drug

    Tetracaine

    go.drugbank.com/drugs/DB09085
    ApprovedInvestigationalVet approved

    Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

    Mixtures: Lidocaine 7% / Tetracaine 7%, Ndc 72934- 5010-4 Benzocaine 20% / Lidocaine 8% / Tetracaine 4%.Synonyms: 2-(dimethylamino)ethyl 4-(butylamino)benzoate, 2-(Dimethylamino)ethyl p-(butylamino)benzoate
  5. Drug

    Eugenol

    go.drugbank.com/drugs/DB09086
    ApprovedInvestigational

    It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control. … Eugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Daclatasvir

    go.drugbank.com/drugs/DB09102
    ApprovedInvestigationalWithdrawn

    Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. … Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV).

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: I-HEP CLASTAVIR 30, I-HEP CLASTAVIR 60
  7. Drug

    Potassium citrate

    go.drugbank.com/drugs/DB09125
    ApprovedInvestigationalVet approved

    Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. … In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis.

    Mixtures: B 6 Plus, Formula No. 2 Plus K LiqProducts: Urocit-K, Polycitra-K
  8. Drug

    Iothalamic acid

    go.drugbank.com/drugs/DB09133
    Approved

    Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.

    Salts: Iothalamate sodium I-125Categories: X-Ray Contrast Activity, X-Ray Contrast Media, Iodinated
  9. Drug

    Sonidegib

    go.drugbank.com/drugs/DB09143
    ApprovedInvestigational

    Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
  10. Drug

    Trypan blue free acid

    go.drugbank.com/drugs/DB09158
    Approved

    Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. … This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.

    Categories: Compounds used in a research, industrial, or household setting