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Displaying results 871 - 880 of 10000 in total
  1. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Insulin glulisine is a biosynthetic, rapid-acting human insulin analogue produced in a non-pathogenic laboratory strain of _Escherichia coli_ (K12).

    Categories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersProducts: Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen, APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN
  2. Target

    Cholecystokinin receptor type A

    go.drugbank.com/bio_entities/BE0000402
    TargetHumans

    This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system … Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system.

    Polypeptides: Cholecystokinin receptor type ASynonyms: CCK-A receptor
  3. Target

    Choline-phosphate cytidylyltransferase A

    go.drugbank.com/bio_entities/BE0000615
    EnzymeTargetHumans

    Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis

    Polypeptides: Choline-phosphate cytidylyltransferase ASynonyms: CT A, CCT A
  4. Target

    Catabolite control protein A

    go.drugbank.com/bio_entities/BE0001530
    TargetBacillus megaterium

    Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.

    Polypeptides: Catabolite control protein A
  5. Target

    Fructose-bisphosphate aldolase A

    go.drugbank.com/bio_entities/BE0001683
    TargetEnzymeHumans

    In addition, also functions as a scaffolding protein (By similarity). … Catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphate and plays a key role in glycolysis and gluconeogenesis (PubMed:14766013).

    Polypeptides: Fructose-bisphosphate aldolase A
  6. Target

    Outer membrane protein A

    go.drugbank.com/bio_entities/BE0002043
    TargetEscherichia coli (strain K12)

    Plays a role in resistance to environmental stress, and a role in outer membrane functionality and cell shape (PubMed:11906175, PubMed:361695). … A very abundant protein, there can be up to 210,000 OmpA molecules per cell (PubMed:24766808).

    Polypeptides: Outer membrane protein ASynonyms: Outer membrane porin A
  7. Target

    DNA gyrase subunit A

    go.drugbank.com/bio_entities/BE0003724
    TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)

    A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.

    Polypeptides: DNA gyrase subunit A
  8. Target

    DNA gyrase subunit A

    go.drugbank.com/bio_entities/BE0008387
    TargetBacillus subtilis (strain 168)

    A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.

    Polypeptides: DNA gyrase subunit A
  9. Target

    Inhibin beta A chain

    go.drugbank.com/bio_entities/BE0010139
    TargetHumans

    Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid

    Polypeptides: Inhibin beta A chainSynonyms: Activin beta-A chain
  10. Target

    Human Arylsulfatase A mRNA

    go.drugbank.com/bio_entities/BE0010214
    TargetHumans