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PD-169316
go.drugbank.com/drugs/DB17040ExperimentalPD-169316 is a p38 MAP kinase inhibitor.[A253062]
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1h-imidazole, Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)-PD-173952
go.drugbank.com/drugs/DB17041ExperimentalPD-173952 is a potent Myt1 kinase inhibitor.[A253067]
Categories: Heterocyclic Compounds, 1-RingSB 224289
go.drugbank.com/drugs/DB17052ExperimentalSB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122]
Categories: Heterocyclic Compounds, 1-RingSynonyms: (1'-methyl-6,7-dihydro-5h-spiro(furo(2,3-f)indole-3,4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)methanone, 6,7-dihydro-1'-methyl-5-((2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-yl)carbonyl)spiro(2h-furo(2,3-f)indole-3(5h),4'-piperidine)Spiperone
go.drugbank.com/drugs/DB17056ExperimentalSpiperone is a dopamine antagonist that binds dopamine and serotonin receptors.[A253142]
TW-37
go.drugbank.com/drugs/DB17059ExperimentalTW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157]
Synonyms: Benzamide, n-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)-, N-(4-((2-(1,1-dimethylethyl)phenyl)sulfonyl)phenyl)-2,3,4-trihydroxy-5-((2-(1-methylethyl)phenyl)methyl)benzamideU-0126
go.drugbank.com/drugs/DB17060ExperimentalU-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.[A253162]
Salts: U-0126-EtOHSynonyms: 1,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)butadiene, Butanedinitrile, bis(amino((2-aminophenyl)thio)methylene)-, (2z,3z)-ZK-93423
go.drugbank.com/drugs/DB17063ExperimentalZK-93423 is a beta-carboline with muscle relaxant activity with agonistic properties at the benzodiazepine receptor.[A253172]
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 9H-Pyrido[3,4-b]indole-3-carboxylicacid, 4-(methoxymethyl)-6-(phenylmethoxy)-, ethyl esterZM-39923
go.drugbank.com/drugs/DB17064ExperimentalZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).[A253177]
Synonyms: 1-propanone, 3-((1-methylethyl)(phenylmethyl)amino)-1-(2-naphthalenyl)-, 3-(benzyl(propan-2-yl)amino)-1-(naphthalen-2-yl)propan-1-oneAutologous Hematopoietic Peripheral Blood Stem Cells
go.drugbank.com/drugs/DB17067InvestigationalAutologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.
αAβ–Gas6
go.drugbank.com/drugs/DB17069ExperimentalIt is made of a single chain variable fragment (scFv) of an Amyloid β (Aβ)-targeting monoclonal antibody fused with a truncated receptor binding domain of growth arrest-specific 6 (Gas6), which is a ligand … for receptor kinases expressed in glial cells.