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Pyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalPyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. … While its use has been approved in the early 1960's by the FDA [A32163], safety and effectiveness of pyrithione zinc has been reported for decades.
Mixtures: Z-plus Shampoo, Neutrogena T/Gel TherapeuticCategories: Heterocyclic Compounds, 1-RingPhenylbutyric acid
go.drugbank.com/drugs/DB06819ApprovedInvestigationalPhenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria fermentation. … It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 4-Phenyl-n-butyric acid, γ-Phenyl-n-butyric acidTiopronin
go.drugbank.com/drugs/DB06823ApprovedTiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. … It is similar to d-penicillamine in use and efficacy, but offers the advantage of far less adverse effects.
Categories: N-substituted Glycines1-Dodecanol
go.drugbank.com/drugs/DB06894Experimental1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals.
Synonyms: Dodecan-1-ol(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol
go.drugbank.com/drugs/DB06943Experimental(3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiol is a solid. This compound belongs to the benzenesulfonamides. … These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring. This substance is known to target disintegrin and metalloproteinase domain-containing protein 17.
Synonyms: (3S)-1-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}pyrrolidine-3-thiolN-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide
go.drugbank.com/drugs/DB06944ExperimentalN-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. This compound belongs to the naphthalenes. … The proteins that N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide targets include cyclin-A2 and cyclin-dependent kinase 2.
Synonyms: N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamideBisphenol A
go.drugbank.com/drugs/DB06973ExperimentalCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Bisphenol A, Bisphenol-AAminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalAminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexProducts: อมิโนฟิลลีน 1 1/2 เกรน, DRAFILYN ZEnoxaparin
go.drugbank.com/drugs/DB01225ApprovedInvestigationalEnoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. … Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.
Products: KLEXANE 10000 IE 100MG O S, CLEXANE TPemoline
go.drugbank.com/drugs/DB01230ApprovedIllicitWithdrawnIn 2005, the Food and Drug Administration (FDA) withdrew approval for pemoline. In March 2005, Abbott Laboratories (Cylert marketer) had discontinued the production of Cylert arguing economic reasons.
Categories: Heterocyclic Compounds, 1-Ring