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Displaying results 881 - 890 of 10000 in total
  1. Drug

    Mepivacaine

    go.drugbank.com/drugs/DB00961
    ApprovedInvestigationalVet approved

    A local anesthetic that is chemically related to bupivacaine but pharmacologically related to lidocaine. It is indicated for infiltration, nerve block, and epidural anesthesia.

    Synonyms: 1-methyl-2',6'-pipecoloxylidide, (+-)-1-Methyl-2',6'-pipecoloxylidideMixtures: Scandonest L, 2% Polocaine Dental With Levonordefrin 1:20,000
  2. Drug

    Rasagiline

    go.drugbank.com/drugs/DB01367
    ApprovedInvestigational

    Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.

    Synonyms: (1R)-N-propargylindan-1-amine, (R)-N-2-Propynyl-1-indanamineCategories: Compounds used in a research, industrial, or household setting
  3. Drug

    Technetium Tc-99m pertechnetate

    go.drugbank.com/drugs/DB09314
    ApprovedInvestigational

    and promptly used for clinical diagnostics. … Currently marketed as the product Drytec, technetium-99m pertechnetate is indicated for imaging of the following tissues: thyroid, salivary gland, urinary bladder (for detection of vesico-ureteral reflux

    Mixtures: POLGENTEC 2-120 GBQ GENERADOR DE RADIONUCLEIDOSCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Lenvatinib

    go.drugbank.com/drugs/DB09078
    ApprovedInvestigational

    However, for patients with RAI-refractory thyroid cancer, treatment options are limited and the prognosis is poor, leading to a push for the development of more targeted therapies such as lenvatinib. … In particular, VEGF has been identified as a crucial regulator of both physiologic and pathologic angiogenesis and increased expression of VEGF is associated with a poor prognosis in many types of cancers

    Products: LENVIMA HARD CAPSULES 10 MG, เล็นวิมา (10 มิลลิกรัม)
  5. Drug

    Eptifibatide

    go.drugbank.com/drugs/DB00063
    ApprovedInvestigational

    Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide that belongs to the class of arginin-glycin-aspartat-mimetics.

    Products: EPTICARD 20 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, INTEGRILIN INYECTABLE 2 MG/ML.
  6. Drug

    Zoledronic acid

    go.drugbank.com/drugs/DB00399
    ApprovedInvestigational

    Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid]. … [A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712]

    Synonyms: (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid, (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acidSalts: Zoledronate D,L-Lysine Monohydrate
  7. Drug

    Evolocumab

    go.drugbank.com/drugs/DB09303
    ApprovedInvestigational

    Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. … PCSK9 is a protein that targets LDL receptors for degradation, therefore reducing the liver's ability to remove LDL-cholesterol (LDL-C), or "bad" cholesterol, from the blood.

    Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, Non-statin Hypolipidemic Agents Indicated for HyperlipidemiaProducts: REPATHA® 140 MG/ML, REPATHA 140 MG/ML SC ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR ENJEKTOR, 1 ADET
  8. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … Phenytoin is classified as a hydantoin derivative and despite its narrow therapeutic index, it is one of the most commonly used anticonvulsants.

    Synonyms: PR-122 (redox-phenytoin), 5,5-Diphenyltetrahydro-1H-2,4-imidazoledioneCategories: Heterocyclic Compounds, 1-Ring, UGT1A1 Substrates with a Narrow Therapeutic Index
  9. Drug

    Tetryzoline

    go.drugbank.com/drugs/DB06764
    Approved

    [A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant. … [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several cases of drug-facilitated sexual assault.[A231764]

    Synonyms: 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole, (RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazoleMixtures: EFEMOLINE 5 ML DAMLA, ISCHEMOL A
  10. Drug

    Allopurinol

    go.drugbank.com/drugs/DB00437
    ApprovedInvestigational

    Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942]. … Allopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705

    Synonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidineProducts: ALLOPURINOL 100 1A PHARMA, ALLOPURINOL AL 100