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Displaying results 881 - 890 of 10000 in total
  1. Drug

    Oxibendazole

    go.drugbank.com/drugs/DB04910
    ExperimentalVet approved

    Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.

    Synonyms: Methyl 5-n-propoxy-2-benzimidazole carbamate, Methyl 5-propoxy-2-benzimidazolecarbamateCategories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Bufotenine

    go.drugbank.com/drugs/DB01445
    ExperimentalIllicit

    Bufotenin has been used as a tool in CNS studies and misused as a psychedelic. … A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics.

    Synonyms: 3-[2-(dimethylamino)ethyl]-5-indolol, 3-[2-(dimethylamino)ethyl]indol-5-olCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists
  3. Drug

    WNT-974

    go.drugbank.com/drugs/DB12561
    Investigational

    WNT974 has been used in trials studying the treatment of Metastatic Colorectal Cancer and Squamous Cell Carcinoma, Head And Neck.

    Synonyms: (2,4'-bipyridine)-5-acetamide, 2',3-dimethyl-N-(5-(2-pyrazinyl)-2-pyridinyl)-Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    HUB-101

    go.drugbank.com/drugs/DB18656
    Experimental

    Synonyms: Adeno-associated viral 2/5 (AAV2/5) vector expressing the human KCNJ13 gene
  5. Drug

    Eniluracil

    go.drugbank.com/drugs/DB03516
    Investigational

    Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’ … Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making it orally available.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-Ethynyluracil
  6. Drug

    Cyclic adenosine monophosphate

    go.drugbank.com/drugs/DB02527
    Investigational

    Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 3',5'-cyclic AMP, Adenosine 3',5'-phosphate
  7. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. … Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).

    Mixtures: RABEDIC 10/75 MG MR KAPSÜL, 30 ADET, AFTOJEL % 0,1 + %3 JEL (5 G)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Drug

    1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea

    go.drugbank.com/drugs/DB07789
    Experimental

    Synonyms: 1-[5-Methyl-2-(trifluoromethyl)furan-3-yl]-3-[5-[2-[[6-(1H-1,2,4-triazol-5-ylamino)pyrimidin-4-yl]amino]ethyl]-1,3-thiazol-2-yl]urea
  9. Drug

    ONO-7579

    go.drugbank.com/drugs/DB17236
    Investigational

    Synonyms: 1-[2-[4-(2-amino-5-chloropyridin-3-yl)phenoxy]pyrimidin-5-yl]-3-[2-methylsulfonyl-5-(trifluoromethyl)phenyl]ureaSalts: ONO-7579 Mono-4-Toluenesulfonate
  10. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201] … [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations.

    Mixtures: OCAM PROTECT 15 MG, OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates