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Ropinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547].
Products: ROPINIROL 1A PHARMA 1MG, ROPINIROL 1A PHARMA 2MGTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawn[A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as a bile acid derivative. … Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration.
Talazoparib
go.drugbank.com/drugs/DB11760ApprovedInvestigationalTalazoparib is an inhibitor of mammalian polyadenosine 5’-diphosphoribose polymerases (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and DNA repair. … [L47236] Developed by Pfizer, talazoparib was first approved by the FDA in October 2018 [A260346] and by the EMA in June 2019.[L47296] It was approved by Health Canada in September 2020.
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexSelenic acid
go.drugbank.com/drugs/DB11068ApprovedIt may be found in over-the-counter daily dietary supplements as a source of [DB11135], an essential trace mineral for human health.
Mixtures: One-A-day Advance Men's, Vp-heme Ob DHACategories: Compounds used in a research, industrial, or household settingDroxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalL-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in clinical trials at the phase III point in the United States (U.S.), Canada, Australia, and throughout Europe … The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension.
Nirsevimab
go.drugbank.com/drugs/DB16258ApprovedInvestigational[A254691] This is due to a modification in the Fc region of nirsevimab that grants it a longer half-time compared to typical monoclonal antibodies. … [L44146] It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step of the viral entry process, and neutralizes several RSV A and B strains.
Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.
Mixtures: INYECCION DE LACTATO DE RINGER, SOLUCION DP-AMINEInternational brands: LiquiCal-D 400Ombitasvir
go.drugbank.com/drugs/DB09296ApprovedInvestigationalOmbitasvir is an inhibitor of NS5A, a protein essential for viral replication and virion assembly [FDA Label]. … Ombutasvir is also available as a fixed-dose combination product with [DB09297] and [DB00503] as the FDA- and Health Canada-approved product Technivie.
Racemethionine
go.drugbank.com/drugs/DB13972ApprovedA preparation of methionine that includes a mixture of D-methionine and L-methionine isomers.
Mixtures: Extra Once A Day, Maximum Once A DaySynonyms: DL-Methionine, DL-MethioninumPyrethrum extract
go.drugbank.com/drugs/DB11087ApprovedPyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. … Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species. Pyrethrum extract is also used used to treat head, body, and pubic lice infections.
Mixtures: Select Brand Lice Killing, Dg Health Lice Killing Maximum StrengthCategories: Compounds used in a research, industrial, or household setting