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Vonicog alfa
go.drugbank.com/drugs/DB12872ApprovedInvestigationalVonicog alfa is a recombinant human von Willebrand factor (rVWF) produced from Chinese hamster ovary cells. … [A264444] Used to treat von Willebrand Disease (vWD), it mimics the biological actions of endogenous VWF,[L51274] which is a critical plasma glycoprotein involved in platelet adhesion and aggregation.
Synonyms: (618-THREONINE,709-ASPARTIC ACID)VON WILLEBRAND FACTOR HOMO SAPIENS (1381A>T,1472H>D VARIANT) BLOOD COAGULATION FACTORMavatrep
go.drugbank.com/drugs/DB12875InvestigationalMavatrep has been used in trials studying the treatment of Osteoarthritis, Knee.
Categories: Heterocyclic Compounds, 2-RingOxatomide
go.drugbank.com/drugs/DB12877ApprovedOxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne.
Categories: Heterocyclic Compounds, 1-RingEltoprazine
go.drugbank.com/drugs/DB12883InvestigationalEltoprazine has been used in trials studying the treatment of Schizophrenia and Cognitive Impairment.
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT2 Receptor AntagonistsDihydrexidine
go.drugbank.com/drugs/DB12890InvestigationalDihydrexidine has been used in trials studying the treatment of SPD, Cocaine-Related Disorders, and Schizotypal Personality Disorder.
Categories: Heterocyclic Compounds, 3-RingFiacitabine
go.drugbank.com/drugs/DB12901InvestigationalFiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Categories: Heterocyclic Compounds, 1-RingZoligratinib
go.drugbank.com/drugs/DB12903InvestigationalCh5183284 has been used in trials studying the treatment of Solid Tumours.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingLY-2334737
go.drugbank.com/drugs/DB12906InvestigationalLY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor.
Categories: Heterocyclic Compounds, 1-RingFactor XIII (human)
go.drugbank.com/drugs/DB12909ApprovedInvestigationalWithin the body, FXIII circulates as a heterotetramer composed of 2 A-subunits and 2 B-subunits (A2B2)[A32363]. … As the half-life of endogenous Factor XIII is long (5-11 days), prophylactic therapy with the replacement of FXIII can be given every 4-6 to maintain hemostasis[A32363].
International brands: Fibrogammin PBimekizumab
go.drugbank.com/drugs/DB12917ApprovedInvestigationalBimekizumab is a humanized monoclonal antibody directed towards IL-17, which was approved for use in the EU on August 20, 2021, for the treatment of plaque psoriasis. … [A244455] It has demonstrated superior efficacy as compared to another IL-17 inhibitor, [secukinumab], as well as [ustekinumab] (an IL-12/23 inhibitor) and [adalimumab] (a TNF inhibitor) in the treatment