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CDX-301
go.drugbank.com/drugs/DB19293InvestigationalCDX-301 is under investigation in clinical trial NCT02129075 (A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma).
177Lu-PSMA-I&T
go.drugbank.com/drugs/DB22176Investigational177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).
Synonyms: [177Lu]Lu-PSMA I&T, 177Lu-PSMA I&TCarbomycin
go.drugbank.com/drugs/DB11383ExperimentalVet approvedThe structure of carbomycin was generated in 1957 by Robert Woodward and later modified in 1965. … This antibacterial is obtained from _Streptomyces halstedii_ and it presents a large inhibitory effect against Gram-positive bacteria and some Mycoplasma strains.
Synonyms: Carbomycin A, Magnamycin ARisvutatug rezetecan
go.drugbank.com/drugs/DB23560InvestigationalIt is under investigation in clinical trial NCT06885034 (A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers … Risvutatug rezetecan (GSK5764227) is a novel investigational B7-H3-targeted antibody-drug conjugate.
(S)-Warfarin
go.drugbank.com/drugs/DB14055InvestigationalS-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.
Sulbutiamine
go.drugbank.com/drugs/DB13416InvestigationalSulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. … The chronic administration of the drug has demonstrated to improve long term memory formation in mice.
MK-8777
go.drugbank.com/drugs/DB18904InvestigationalMK-8777 is under investigation in clinical trial NCT00610649 (Trial to Determine the Maximum Tolerated Dose (MTD) Based on Safety and Tolerability, of Org 26576 in Participants With Major Depressive Disorder
Venglustat
go.drugbank.com/drugs/DB14966InvestigationalVenglustat is under investigation in clinical trial NCT01674036 (Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men).
Trigonellamide
go.drugbank.com/drugs/DB11710InvestigationalTrigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers).
AZD-5991
go.drugbank.com/drugs/DB14792InvestigationalAZD-5991 is under investigation in clinical trial NCT03218683 (Study of AZD5991 in Relapsed or Refractory Haematologic Malignancies.).