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Displaying results 8911 - 8920 of 10000 in total
  1. Drug

    APL-030

    go.drugbank.com/drugs/DB18735
    Experimental

    APL-030 is a orally-active small molecule inhibitor of GCN2.

    Synonyms: N-(4-((2-aminopyrimidin-5-yl)ethynyl)-3-fluoropyridin-2-yl)-5-chloro-2-methoxypyridine-3-sulfonamide
  2. Drug

    BA1301

    go.drugbank.com/drugs/DB19390
    Investigational

    BA1301 is an anti-Claudin18.2 monoclonal antibody conjugated with Duostatin-5.

  3. Drug

    YMI024

    go.drugbank.com/drugs/DB32602
    Experimental

    YMI024 is a drug being investigated for inflammation-driven diseases.[L56081]

  4. Drug

    MB07811

    go.drugbank.com/drugs/DB05192
    Investigational

    MB07811, a small molecule that is administered orally, has been extensively studied preclinically and is currently undergoing clinical testing. … MB07811 is the first of a novel class of product candidates discovered by Metabasis designed to lower serum cholesterol and triglycerides.

  5. Drug

    RGN6024

    go.drugbank.com/drugs/DB33059
    Experimental

    RGN6024, also known as RGN-6024 or RGNi6024, is a synthetic small-molecule tubulin destabilizer from Reglagene. … RGN6024 remains investigational and is not an approved drug.

  6. Drug

    AICA ribonucleotide

    go.drugbank.com/drugs/DB01700
    Investigational

    5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent … The drug was first used in the 1980s as a method to preserve blood flow to the heart during surgery and is currently of interest as a potential treatment for diabetes by increasing the metabolic activity

    Synonyms: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, 1-(5'-phosphoribosyl)-5-amino-4-imidazolecarboxamideCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    TM30339

    go.drugbank.com/drugs/DB05085
    Experimental

    TM30339 thus imitates a natural mechanism, a satiety signal from the gastrointestinal system involved in the regulation of food intake in humans. TM30339 is developed for the treatment of obesity. … TM30339 is an analogue of the natural hormone Pancreatic Polypeptide (PP), which is released in connection with meals.

  8. Drug

    SCB-2019

    go.drugbank.com/drugs/DB15805
    Investigational

    SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19. … As of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908) to test the safety and immunogenicity of the vaccine.

  9. Drug

    Brilaroxazine

    go.drugbank.com/drugs/DB09226
    Investigational

    Brilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. … As of May 2015, it is in phase III clinical trials for schizophrenia.

    Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsSynonyms: 6-(4-(4-(2,3-Dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo(b)(1,4)oxazin-3(4H)-one
  10. Drug

    Lotiglipron

    go.drugbank.com/drugs/DB21631
    Investigational

    Lotiglipron is a small molecule drug. The usage of the INN stem '-glipron' in the name indicates that Lotiglipron is a glucagon-like peptide 1 receptor (GLPIR) agonist. … Lotiglipron is under investigation in clinical trial NCT05579977 (Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People